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NCT05839041 · ClinicalTrials.gov registry record · Phase 2
A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
A Phase 2 study of Macular Degeneration and Geographic Atrophy of the Macula, sponsored by Aviceda Therapeutics.
- Active
- Registry status
- Phase 2
- Development phase
- 300
- Enrollment target
- 20
- Study locations
NCT05839041 is a Phase 2 study of Macular Degeneration and Geographic Atrophy of the Macula that is active but no longer recruiting, run by Aviceda Therapeutics. The registered enrollment target is 300 participants, above the 168-participant average among 26 other Macular Degeneration trials with a reported enrollment target (79% higher). The trial reports 20 study locations across 5 states.
The verdict
NCT05839041, a Phase 2 study of Macular Degeneration and Geographic Atrophy of the Macula, is active but no longer recruiting, sponsored by Aviceda Therapeutics.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 300 participants
- Enrollment target
- 20
- Study locations
Study Summary
Investigate the Safety, Pharmacokinetics, and Treatment effects of Single and Multi-dose of Intravitreal AVD-104 in participants with geographic atrophy secondary to age-related macular degeneration.
Conditions Studied
Interventions
- DRUG AVD-104
- DRUG Avacincaptad
Study Locations (20)
California
- Retina Vitreous Associates Medical Group - Beverly Hills
- Macula & Retina Institute - Glendale
- Northern California Retina Vitreous Associates - Mountain View
- Kaiser Permanente - Riverside
- Retinal Consultants Medical Group, Inc. - Sacramento
- Retinal Consultants Medical Group - Sacramento
- West Coast Retina - San Francisco
- RCA: California Retina Consultants - Santa Barbara
Florida
- Rand Eye Institute - Deerfield Beach
- Retina Group of Florida - Fort Lauderdale
- Florida Retina Institute - Orlando
- Retina Specialty Institute - Pensacola
- Retina Vitreous Associates of Florida - St. Petersburg
- Southern Vitreoretinal Associates - Tallahassee
- Center for Retina & Macular Disease - Winter Haven
Arizona
- Associated Retina Consultants - Gilbert
- Arizona Retina and Vitreous Consultants - Phoenix
- Associated Retina Consultants - Scottsdale
Connecticut
- Retina Group of New England, PC - Waterford
Georgia
- Southeast Retina Center - Augusta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2023-05-02 |
| Est. Completion | 2026-10 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05839041
The ClinicalTrials.gov registry entry for NCT05839041 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 168-participant average among 26 other Macular Degeneration trials with a reported enrollment target (79% higher). The listed sponsor is Aviceda Therapeutics, which has 2 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Macular Degeneration appearing as the primary indexed condition, and to 2 interventions - of which AVD-104 is the first listed.
NCT05839041 reports 20 study locations spanning 5 distinct geographic areas - top geographies include California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT05839041 about?
NCT05839041 is a clinical study titled "A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)". Investigate the Safety, Pharmacokinetics, and Treatment effects of Single and Multi-dose of Intravitreal AVD-104 in participants with geographic atrophy secondary to age-related macular degeneration.
What is the current status of trial NCT05839041?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 300 participants. The study started on 2023-05-02. Estimated completion is 2026-10.
What conditions does trial NCT05839041 study?
This clinical trial studies the following conditions: Macular Degeneration, Geographic Atrophy of the Macula.
What interventions are being tested in trial NCT05839041?
The interventions under investigation include: AVD-104 (DRUG), Avacincaptad (DRUG).
Who is sponsoring clinical trial NCT05839041?
This trial is sponsored by Aviceda Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05839041 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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