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NCT05819073 · ClinicalTrials.gov registry record · NA
Astringency and Oral Health
A NA study, sponsored by Rutgers, The State University of New Jersey.
- Completed
- Registry status
- NA
- Development phase
- 49
- Enrollment target
NCT05819073 is a NA study that has completed, run by Rutgers, The State University of New Jersey. The registered enrollment target is 49 participants.
The verdict
NCT05819073, a NA study, has completed, sponsored by Rutgers, The State University of New Jersey.
- COMPLETED
- Registry status
- NA
- Development phase
- 49 participants
- Enrollment target
Study Summary
The perception of astringency is thought to involve the interaction between tannins and salivary proteins. However, the mechanisms underlying this interaction are poorly understood. The tannins' subclass known as type A proanthocyanidins seems to have a positive effect on human health. Despite that, humans show large individual differences in the sensory perception and acceptance of astringent foods such as tea, wine and chocolate suggesting that this variation may have a genetic basis. Salivary proteins play an essential role both in affecting oral taste perception and in maintaining a healthy oral environment. Diverse microorganisms inhabit the oral cavity. The interactions between oral microbiota, host and environmental factors influence microbial homeostasis and ultimately human oral health. Understanding individual differences in salivary proteins, oral microbiome and the mechanisms by which tannins evoke the perception of astringency could provide important insights into the role of these compounds in human nutrition and health.
Interventions
- OTHER Plain water
- OTHER CPE
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2022-11-01 |
| Est. Completion | 2023-11-14 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05819073
The ClinicalTrials.gov registry entry for NCT05819073 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 49 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rutgers, The State University of New Jersey, which has 413 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Plain water is the first listed.
NCT05819073 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05819073 about?
NCT05819073 is a clinical study titled "Astringency and Oral Health". The perception of astringency is thought to involve the interaction between tannins and salivary proteins. However, the mechanisms underlying this interaction are poorly understood. The tannins' subclass known as type A proanthocyanidins seems to have a positive effect on human health. Despite that,...
What is the current status of trial NCT05819073?
This trial is currently completed. It is a NA study. The enrollment target is 49 participants. The study started on 2022-11-01. Estimated completion is 2023-11-14.
What interventions are being tested in trial NCT05819073?
The interventions under investigation include: Plain water (OTHER), CPE (OTHER).
Who is sponsoring clinical trial NCT05819073?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
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