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NCT05818189 · ClinicalTrials.gov registry record · NA
Cortical Correlates of Gait in Parkinson's Disease: Impact of Medication and Cueing
A NA study of Parkinson Disease, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05818189: Recruiting NA study of Parkinson Disease, sponsored by Oregon Health and Science University.
NCT05818189 is a NA study of Parkinson Disease that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 60 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05818189, a NA study of Parkinson Disease, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to determine the effects of a novel, personalized, tactile cueing system on gait automaticity. The researchers hypothesized that step-synchronized tactile cueing will reduce prefrontal cortex activity (improve automaticity) and improve gait variability (as well as gait speed). The researchers predict that improved automaticity with improved gait variability will be associated with increased activation of other than prefrontal cortical areas while walking (i.e., sensory-motor). To determine the effects of cueing, 60 participants with PD from will be randomized into one, of two, cueing interventions: 1) personalized, step-synchronized tactile cueing and 2) tactile cueing at fixed intervals as an active control group. In addition, the researchers will explore the feasibility and potential benefits of independent use of tactile cueing during a week in daily life for a future clinical trial. This project will characterize the cortical correlates of gait automaticity, the changes in gait automaticity with cueing in people with Parkinson's Disease, and how these changes translate to improvement in gait and turning. The long-term goal is to unravel the mechanisms of impaired gait automaticity in Parkinson's Disease.
Primary Outcome
Oxygenated hemoglobin over the prefrontal cortex measures by fNIRS
Conditions Studied
Interventions
- DEVICE Personalized tactile cueing
- DEVICE Fixed tactile cueing
Study Locations (1)
Oregon
- Oregon Health and Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-01-15 |
| Est. Completion | 2028-01-31 |
| Phase | NA |
What NCT05818189 shows while recruiting
NCT05818189 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 2 interventions - of which Personalized tactile cueing is the first listed.
NCT05818189 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT05818189 about?
NCT05818189 is a clinical study titled "Cortical Correlates of Gait in Parkinson's Disease: Impact of Medication and Cueing". The purpose of the study is to determine the effects of a novel, personalized, tactile cueing system on gait automaticity. The researchers hypothesized that step-synchronized tactile cueing will reduce prefrontal cortex activity (improve automaticity) and improve gait variability (as well as gait sp...
What is the current status of trial NCT05818189?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-01-15. Estimated completion is 2028-01-31.
What conditions does trial NCT05818189 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT05818189?
The interventions under investigation include: Personalized tactile cueing (DEVICE), Fixed tactile cueing (DEVICE).
Who is sponsoring clinical trial NCT05818189?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05818189 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05818189's enrollment target sits among peer trials
60 125th of 297 higher than 154 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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