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NCT05801861 · ClinicalTrials.gov registry record · NA
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
A NA study of Spatial Navigation, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05801861: Recruiting NA study of Spatial Navigation, sponsored by Rutgers, The State University of New Jersey.
NCT05801861 is a NA study of Spatial Navigation that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05801861, a NA study of Spatial Navigation, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is believed to index the sensitivity of the parahippocampal cortex to spatial context. Here the investigators will asked whether this electrophysiological signal can be modulated up or down using TMS while participants engage in virtual navigation tasks, and if so, whether it would affect the spatial encoding of rewards and subsequent choices during task performance.
Primary Outcome
Right posterior theta (RPT: 4-8 hz) is a scalp recorded brain oscillation sensitive to spatial processing of reward stimulus presented during navigation tasks. RPT will be measured during the presentation of the reward stimulus (Reward, No-reward) during virtual navigation. A time-frequency analysis will be used to measure RPT power for each electrode by averaging the single-trial EEG according to feedback type (reward and no-reward) during the navigation tasks. The size of the RPT will be deter
Conditions Studied
Interventions
- DEVICE Active 10-Hz TMS to the parietal cortex
- DEVICE Active single pulse TMS to the parietal cortex
- DEVICE Sham 10-Hz TMS to the right parietal cortex
- DEVICE Sham single-pulse rTMS the rigt parietal cortex
Study Locations (1)
New Jersey
- Rutgers University - Newark - Newark
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-03-24 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
What NCT05801861 shows while recruiting
NCT05801861 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Spatial Navigation appearing as the primary indexed condition, and to 4 interventions - of which Active 10-Hz TMS to the parietal cortex is the first listed.
NCT05801861 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT05801861 about?
NCT05801861 is a clinical study titled "Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation". Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is believed to index the sensitivity of the parahippocampal cortex to spat...
What is the current status of trial NCT05801861?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-03-24. Estimated completion is 2026-08-31.
What conditions does trial NCT05801861 study?
This clinical trial studies the following conditions: Spatial Navigation.
What interventions are being tested in trial NCT05801861?
The interventions under investigation include: Active 10-Hz TMS to the parietal cortex (DEVICE), Active single pulse TMS to the parietal cortex (DEVICE), Sham 10-Hz TMS to the right parietal cortex (DEVICE), Sham single-pulse rTMS the rigt parietal cortex (DEVICE).
Who is sponsoring clinical trial NCT05801861?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05801861 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05801861's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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