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NCT05799872 · ClinicalTrials.gov registry record · NA
Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa
A NA study of Anorexia Nervosa, sponsored by Virginia Commonwealth University.
- Recruiting
- Registry status
- NA
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT05799872: Recruiting NA study of Anorexia Nervosa, sponsored by Virginia Commonwealth University.
NCT05799872 is a NA study of Anorexia Nervosa that is actively recruiting participants, run by Virginia Commonwealth University. The registered enrollment target is 90 participants, below the 948-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05799872, a NA study of Anorexia Nervosa, is actively recruiting participants, sponsored by Virginia Commonwealth University.
- RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators will recruit individuals with broadly-defined AN (n = 80) who are currently in or have recently participated in higher-level eating disorder treatment (e.g., residential, partial hospitalization/day treatment, intensive outpatient treatment). Interested participants will sign consent, complete eligibility assessments, and will be randomized to receive Positive Affect Treatment for Anorexia Nervosa (PAT-AN) or Psychoeducation and Behavioral Therapy (PBT) through teletherapy shortly following discharge from higher level of care. Participants can participate in most other forms of outpatient treatment while receiving the research intervention. Participants will engage in 24 weeks of PAT-AN or PBT starting in the first 3 months post-discharge. At each session, the investigators will complete brief measures assessing treatment acceptability, affect, and eating disorder symptoms. Participants will also complete an assessment battery of self-report, EMA, and neurocognitive measures evaluating primary outcomes (BMI; eating disorder symptoms), secondary outcomes (depression, anxiety, and suicidality), and presumed treatment mechanisms at baseline, end of treatment (EOT), and 3-month follow-up (FU). All assessments will be remotely delivered via HIPAA-compliant platforms.
Primary Outcome
Objective height will be captured through guided measurement at baseline. Objective weight will be measured throughout on a blind smartscale, which will transfer weight data directly to the research team by wireless internet without providing an outward display of weight to participants. Participants will have a smartscale shipped to their home. They will measure their weight at baseline and following treatment on the scale in standard street clothes (no outer garments or shoes) while on a video
Conditions Studied
Interventions
- BEHAVIORAL Positive Affect Treatment for Anorexia Nervosa (PAT-AN):
- BEHAVIORAL Psychoeducational and Behavioral Therapy (PBT)
Study Locations (1)
Virginia
- Virginia Commonwealth University - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2023-12-06 |
| Est. Completion | 2026-10-30 |
| Phase | NA |
What NCT05799872 shows while recruiting
NCT05799872 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 948-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Anorexia Nervosa appearing as the primary indexed condition, and to 2 interventions - of which Positive Affect Treatment for Anorexia Nervosa (PAT-AN): is the first listed.
NCT05799872 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT05799872 about?
NCT05799872 is a clinical study titled "Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa". The investigators will recruit individuals with broadly-defined AN (n = 80) who are currently in or have recently participated in higher-level eating disorder treatment (e.g., residential, partial hospitalization/day treatment, intensive outpatient treatment). Interested participants will sign conse...
What is the current status of trial NCT05799872?
This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2023-12-06. Estimated completion is 2026-10-30.
What conditions does trial NCT05799872 study?
This clinical trial studies the following conditions: Anorexia Nervosa.
What interventions are being tested in trial NCT05799872?
The interventions under investigation include: Positive Affect Treatment for Anorexia Nervosa (PAT-AN): (BEHAVIORAL), Psychoeducational and Behavioral Therapy (PBT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05799872?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05799872 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05799872's enrollment target sits among peer trials
90 11th of 43 higher than 31 of 43 other Anorexia Nervosa trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anorexia Nervosa trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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