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NCT05797506 · ClinicalTrials.gov registry record · Phase 2

Safety, Feasibility and Efficacy of Sulforaphane (Avmacol Extra Strength) in Chronic Kidney Disease

A Phase 2 study of Chronic Kidney Disease Stage 3 and Chronic Kidney Disease Stage 4, sponsored by University of Rochester.

Active
Registry status
Phase 2
Development phase
100
Enrollment target
1
Study location

NCT05797506 is a Phase 2 study of Chronic Kidney Disease Stage 3 and Chronic Kidney Disease Stage 4 that is active but no longer recruiting, run by University of Rochester. The registered enrollment target is 100 participants, below the 7,425-participant average among 3 other Chronic Kidney Disease Stage 3 trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05797506, a Phase 2 study of Chronic Kidney Disease Stage 3 and Chronic Kidney Disease Stage 4, is active but no longer recruiting, sponsored by University of Rochester.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

The Sulforaphane Production System® in Avmacol Extra Strength (ES) supplies broccoli seed extract (glucoraphanin) and Myrosimax® (Active Myrosinase Enzyme) which helps promote sulforaphane production in your body. The investigators hypothesize that daily intake of Avmacol ES can decrease kidney disease progression rate and decrease markers of oxidative stress and inflammation in Chronic Kidney Disease (CKD) patients. They will test this hypothesis in a randomized, double-blind, placebo controlled Phase 2 clinical trial. This proposed study has been funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), R01 DK128677.

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DRUG Sulforaphane (Avmacol Extra Strength)

Study Locations (1)

New York

  • University of Rochester Medical Center - Rochester

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2023-05-03
Est. Completion 2025-12-31
Phase Phase 2

Sponsor

University of Rochester

636 total trials

What the Registry Record Tells You About NCT05797506

The ClinicalTrials.gov registry entry for NCT05797506 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 7,425-participant average among 3 other Chronic Kidney Disease Stage 3 trials with a reported enrollment target (99% lower). The listed sponsor is University of Rochester, which has 636 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Chronic Kidney Disease Stage 3 appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05797506 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT05797506 about?

NCT05797506 is a clinical study titled "Safety, Feasibility and Efficacy of Sulforaphane (Avmacol Extra Strength) in Chronic Kidney Disease". The Sulforaphane Production System® in Avmacol Extra Strength (ES) supplies broccoli seed extract (glucoraphanin) and Myrosimax® (Active Myrosinase Enzyme) which helps promote sulforaphane production in your body. The investigators hypothesize that daily intake of Avmacol ES can decrease kidney dise...

What is the current status of trial NCT05797506?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2023-05-03. Estimated completion is 2025-12-31.

What conditions does trial NCT05797506 study?

This clinical trial studies the following conditions: Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4.

What interventions are being tested in trial NCT05797506?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Sulforaphane (Avmacol Extra Strength) (DRUG).

Who is sponsoring clinical trial NCT05797506?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05797506 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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