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NCT05795452 · ClinicalTrials.gov registry record
Environmental Mixtures, Cognitive Control and Reward Processes, and Risk for Psychiatric Problems in Adolescence
A clinical trial of Psychiatric Problem, sponsored by Ohio State University.
- Active
- Registry status
- 250
- Enrollment target
- 1
- Study location
NCT05795452: Active study of Psychiatric Problem, sponsored by Ohio State University.
NCT05795452 is a study of Psychiatric Problem that is active but no longer recruiting, run by Ohio State University. The registered enrollment target is 250 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05795452, a study of Psychiatric Problem, is active but no longer recruiting, sponsored by Ohio State University.
- ACTIVE NOT RECRUITING
- Registry status
- 250 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to examine the cognitive and neural pathways underlying the joint impact of chemical and social exposures on two aspects of cognitive function: cognitive control and reward processing. The investigators will use high resolution, multi-band resting state and task functional magnetic resonance imaging (fMRI) as well as neuromelanin stain MRI to identify pathways through which exposure to a mixture of prenatal chemical and early life social exposures alters brain function and behavior. Specifically, the investigators will leverage extant prenatal exposure data (N=550) from the Columbia Center for Children's Environmental Health (CCCEH) Mothers and Newborns (MN) birth cohort and study symptoms and brain function in adolescence.
Primary Outcome
This is a 112-question scale for adolescents about their own behavioral functioning. It has a Likert-like scoring format and multiple syndrome and DSM-oriented scales, with higher scores indicating more symptoms. Raw scores are converted to T scores with a mean of 50 and standard deviation of 10. The range is 0 to 90.
Conditions Studied
Study Locations (1)
New York
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2022-02-20 |
| Est. Completion | 2026-05 |
What the registry record for NCT05795452 still lists
NCT05795452 is an observational study that tracks outcomes without assigning an intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with Psychiatric Problem appearing as the primary indexed condition, and to 0 interventions.
NCT05795452 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05795452 about?
NCT05795452 is a clinical study titled "Environmental Mixtures, Cognitive Control and Reward Processes, and Risk for Psychiatric Problems in Adolescence". This study aims to examine the cognitive and neural pathways underlying the joint impact of chemical and social exposures on two aspects of cognitive function: cognitive control and reward processing. The investigators will use high resolution, multi-band resting state and task functional magnetic r...
What is the current status of trial NCT05795452?
This trial is currently active not recruiting. The enrollment target is 250 participants. The study started on 2022-02-20. Estimated completion is 2026-05.
What conditions does trial NCT05795452 study?
This clinical trial studies the following conditions: Psychiatric Problem.
Who is sponsoring clinical trial NCT05795452?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05795452 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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