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NCT05792722 · ClinicalTrials.gov registry record · NA
Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy
A NA study of Bladder Cancer, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 2
- Study locations
NCT05792722: Recruiting NA study of Bladder Cancer, sponsored by Johns Hopkins University.
NCT05792722 is a NA study of Bladder Cancer that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 70 participants, below the 12,753-participant average among 175 other Bladder Cancer trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05792722, a NA study of Bladder Cancer, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 2
- Study locations
Study Summary
The purpose of this clinical trial is to determine if prostate-capsule-sparing cystectomy improves functional outcomes without comprising oncologic outcomes in male patients receiving a radical cystectomy. Patients will be randomized to one of two groups: prostate capsule-sparing radical cystectomy or nerve-sparing radical cystectomy. Patients will be monitored following standard of care guidelines and clinical data will be collected. Patients in both groups will be asked to complete an erectile function questionnaire at multiple timepoints. Patients who receive an orthotopic neobladder will be asked to complete a questionnaire to monitor urinary function at multiple timepoints. Patient adverse events will be monitored to ensure patients safety.
Primary Outcome
Comparison of functional outcomes focusing on preservation of erectile function in patients undergoing cystectomy for bladder cancer. Functional Outcomes will be measured by the Sexual Health Inventory for Men (SHIM) Questionnaire. The Sexual Health Inventory for Men defines the following ranges of Erectile Dysfunction (ED): 1-7 is Severe ED, 8-11 Moderate ED, 12-16 Mild to Moderate ED, and 17 to 21 is Mild ED.
Conditions Studied
Interventions
- PROCEDURE Prostate capsule-sparing radical cystectomy
- PROCEDURE Nerve sparing radical cystectomy
Study Locations (2)
District of Columbia
- Sibley Memorial Hospital - Washington D.C.
Maryland
- Johns Hopkins Hospital - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2023-10-25 |
| Est. Completion | 2029-07 |
| Phase | NA |
What NCT05792722 shows while recruiting
NCT05792722 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 12,753-participant average among 175 other Bladder Cancer trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Bladder Cancer appearing as the primary indexed condition, and to 2 interventions - of which Prostate capsule-sparing radical cystectomy is the first listed.
NCT05792722 reports a single indexed study location in District of Columbia, Maryland.
Frequently Asked Questions
What is clinical trial NCT05792722 about?
NCT05792722 is a clinical study titled "Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy". The purpose of this clinical trial is to determine if prostate-capsule-sparing cystectomy improves functional outcomes without comprising oncologic outcomes in male patients receiving a radical cystectomy. Patients will be randomized to one of two groups: prostate capsule-sparing radical cystectomy ...
What is the current status of trial NCT05792722?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2023-10-25. Estimated completion is 2029-07.
What conditions does trial NCT05792722 study?
This clinical trial studies the following conditions: Bladder Cancer.
What interventions are being tested in trial NCT05792722?
The interventions under investigation include: Prostate capsule-sparing radical cystectomy (PROCEDURE), Nerve sparing radical cystectomy (PROCEDURE).
Who is sponsoring clinical trial NCT05792722?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05792722 being conducted?
This trial has 2 study locations across District of Columbia, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05792722's enrollment target sits among peer trials
70 99th of 175 higher than 75 of 175 other Bladder Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bladder Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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