Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05783362 · ClinicalTrials.gov registry record · NA
Pain Modulation Effectiveness (PME)
A NA study, sponsored by University of Florida.
- Completed
- Registry status
- NA
- Development phase
- 60
- Enrollment target
NCT05783362 is a NA study that has completed, run by University of Florida. The registered enrollment target is 60 participants.
The verdict
NCT05783362, a NA study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
Study Summary
Conditioned pain modulation (CPM) is the behavioral measure of diffuse noxious inhibitory control (DNIC), an endogenous pain inhibitory pathway in which pain inhibits pain. Conditioned pain modulation is less efficient in individuals with chronic pain conditions, and it is a predictor for the development of chronic pain. Continuous stimulation of central/cortical mechanisms through engaging CPM might alter pain processing and improve pain inhibition. Healthy participants will be randomly assigned to one of three groups: High Exposure (HE), Low Exposure (LE), and No Exposure (NE). Pre-and post-intervention pain sensitivity including conditioned pain modulation will be assessed. The study will assess the central pain modulatory mechanisms (measured by CPM) that have differential changes in participants who receive high exposure CPM as an intervention from those who receive low or no exposure. The study will also assess the magnitude and efficiency of CPM contributing additional variance to a regression model predicting pain sensitivity after positive and negative affect, pain anxiety, and depression are considered in the model, establishing measures of central pain processing, like CPM, as unique contributors to pain intensity.
Interventions
- BEHAVIORAL Conditioned Pain Modulation (CPM)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2023-08-25 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05783362
The ClinicalTrials.gov registry entry for NCT05783362 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Conditioned Pain Modulation (CPM) is the first listed.
NCT05783362 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05783362 about?
NCT05783362 is a clinical study titled "Pain Modulation Effectiveness (PME)". Conditioned pain modulation (CPM) is the behavioral measure of diffuse noxious inhibitory control (DNIC), an endogenous pain inhibitory pathway in which pain inhibits pain. Conditioned pain modulation is less efficient in individuals with chronic pain conditions, and it is a predictor for the develo...
What is the current status of trial NCT05783362?
This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2023-04-01. Estimated completion is 2023-08-25.
What interventions are being tested in trial NCT05783362?
The interventions under investigation include: Conditioned Pain Modulation (CPM) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05783362?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.