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NCT05775601 · ClinicalTrials.gov registry record · Early Phase 1
18F-LY3950321-01 Biodistribution and Safety Study
A Early Phase 1 study, sponsored by Avid Radiopharmaceuticals.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 6
- Enrollment target
NCT05775601: Completed Early Phase 1 study, sponsored by Avid Radiopharmaceuticals.
NCT05775601 is a Early Phase 1 study that has completed, run by Avid Radiopharmaceuticals. The registered enrollment target is 6 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05775601, a Early Phase 1 study, has completed, sponsored by Avid Radiopharmaceuticals.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 6 participants
- Enrollment target
Study Summary
18F-LY3950321 (also known as 18F-MNI-1256) is a radiolabeled positron emission tomography (PET) tracer targeting granzyme B. The overall goal of this protocol is to evaluate the safety, tolerability, and radiation dosimetry of 18F-LY3950321.
Primary Outcome
Radiation dose estimates. Distribution data will be utilized in the MIRD calculations of target organ radiation absorbed dose with correction from urine assays and standard GI kinetic models in Organ Level Internal Dose Assessment (OLINDA). Standard Medical Internal Radiation Dose (MIRD) assumptions will be incorporated in dosimetry models for determination of radiation absorbed doses in target organs and whole-body.
Interventions
- PROCEDURE PET Scan
- DRUG 18F-LY3950321
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2023-02-28 |
| Est. Completion | 2023-04-04 |
| Phase | Early Phase 1 |
What the finished NCT05775601 record still lists
NCT05775601 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 2 interventions - of which PET Scan is the first listed.
NCT05775601 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05775601 about?
NCT05775601 is a clinical study titled "18F-LY3950321-01 Biodistribution and Safety Study". 18F-LY3950321 (also known as 18F-MNI-1256) is a radiolabeled positron emission tomography (PET) tracer targeting granzyme B. The overall goal of this protocol is to evaluate the safety, tolerability, and radiation dosimetry of 18F-LY3950321.
What is the current status of trial NCT05775601?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 6 participants. The study started on 2023-02-28. Estimated completion is 2023-04-04.
What interventions are being tested in trial NCT05775601?
The interventions under investigation include: PET Scan (PROCEDURE), 18F-LY3950321 (DRUG).
Who is sponsoring clinical trial NCT05775601?
This trial is sponsored by Avid Radiopharmaceuticals, which has 42 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05775601's enrollment target sits among peer trials
6 1846th of 2000 higher than 114 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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