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NCT05774678 · ClinicalTrials.gov registry record · Phase 3
Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation
A Phase 3 study of Breast Cancer, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 126
- Enrollment target
- 1
- Study location
NCT05774678: Recruiting Phase 3 study of Breast Cancer, sponsored by M.D. Anderson Cancer Center.
NCT05774678 is a Phase 3 study of Breast Cancer that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 126 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05774678, a Phase 3 study of Breast Cancer, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 126 participants
- Enrollment target
- 1
- Study location
Study Summary
To compare the outcomes of and responses to 2 different radiation therapy schedules (the standard radiation amount and number of doses versus less radiation and fewer doses) that are being given before having breast cancer surgery (cancer removal and reconstruction).
Conditions Studied
Interventions
- RADIATION Group 1 (preoperative radiation hypofractionated)
- OTHER Group 2 (preoperative radiation conventionally fractionated)
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 126 participants |
| Start Date | 2023-04-05 |
| Est. Completion | 2028-11-01 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05774678
The ClinicalTrials.gov registry entry for NCT05774678 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 126 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (96% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Group 1 (preoperative radiation hypofractionated) is the first listed.
NCT05774678 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT05774678 about?
NCT05774678 is a clinical study titled "Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation". To compare the outcomes of and responses to 2 different radiation therapy schedules (the standard radiation amount and number of doses versus less radiation and fewer doses) that are being given before having breast cancer surgery (cancer removal and reconstruction).
What is the current status of trial NCT05774678?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 126 participants. The study started on 2023-04-05. Estimated completion is 2028-11-01.
What conditions does trial NCT05774678 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT05774678?
The interventions under investigation include: Group 1 (preoperative radiation hypofractionated) (RADIATION), Group 2 (preoperative radiation conventionally fractionated) (OTHER).
Who is sponsoring clinical trial NCT05774678?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05774678 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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