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NCT05767749 · ClinicalTrials.gov registry record · Phase 4
Split Face Study of the Duration of Local Anesthetics
A Phase 4 study, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- Phase 4
- Development phase
- 75
- Enrollment target
NCT05767749: Completed Phase 4 study, sponsored by Weill Medical College of Cornell University.
NCT05767749 is a Phase 4 study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 75 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05767749, a Phase 4 study, has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 75 participants
- Enrollment target
Study Summary
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for. This study will compare a short-acting anesthetic, lidocaine with epinephrine, to one of two long-acting anesthetics (ropivacaine or bupivacaine). This study will also directly compare the duration of actions of ropivacaine and bupivacaine. The investigators hypothesize that the duration of anesthesia of short-acting anesthetics will not differ significantly from long-acting anesthetics at a single site and there will not be a significant difference between the two long-acting anesthetics at a single site.
Primary Outcome
To determine whether the time to return to baseline sensation differs significantly between each pair of anesthetics, the investigators will measure the time to return to baseline sensation at each anesthetized site by asking participants at 15 minute intervals if they can feel a sharp sensation at the site. Sterile needles will be used. The return of the sensitivity will be determined using binary outcomes (yes/no) and recorded on a standardized template. The maximum difference in anesthetic du
Interventions
- DRUG Ropivacaine 0.5% Injectable Solution
- DRUG Bupivacaine 0.5% Injectable Solution
- DRUG lidocaine + epinephrine 1:100,000
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2023-03-14 |
| Est. Completion | 2023-07-31 |
| Phase | Phase 4 |
What the finished NCT05767749 record still lists
NCT05767749 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 3 interventions - of which Ropivacaine 0.5% Injectable Solution is the first listed.
NCT05767749 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05767749 about?
NCT05767749 is a clinical study titled "Split Face Study of the Duration of Local Anesthetics". This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for. This study will compare a short-acting anesthetic, lidocaine with epinephrine, to one of two long-acting anesthetics (ropivacaine or bupivacaine). This stud...
What is the current status of trial NCT05767749?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 75 participants. The study started on 2023-03-14. Estimated completion is 2023-07-31.
What interventions are being tested in trial NCT05767749?
The interventions under investigation include: Ropivacaine 0.5% Injectable Solution (DRUG), Bupivacaine 0.5% Injectable Solution (DRUG), lidocaine + epinephrine 1:100,000 (DRUG).
Who is sponsoring clinical trial NCT05767749?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05767749's enrollment target sits among peer trials
75 1002nd of 2000 higher than 974 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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