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NCT05766774 · ClinicalTrials.gov registry record · NA
FEED-Cystic Fibrosis (FEED-CF)
A NA study of Cystic Fibrosis and Cystic Fibrosis-related Diabetes, sponsored by Emory University.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05766774: Recruiting NA study of Cystic Fibrosis and Cystic Fibrosis-related Diabetes, sponsored by Emory University.
NCT05766774 is a NA study of Cystic Fibrosis and Cystic Fibrosis-related Diabetes that is actively recruiting participants, run by Emory University. The registered enrollment target is 60 participants, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05766774, a NA study of Cystic Fibrosis and Cystic Fibrosis-related Diabetes, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to determine the extent to which excess dietary sugars serve as a precipitating factor in glucose intolerance in adults with cystic fibrosis (CF), a population at especially high risk for a unique form of diabetes (CF-related diabetes, CFRD) and with standard-of-care dietary recommendations (high-calorie, high-fat) that conflict with recommendations for other forms of diabetes. This trial will investigate if the typical high-sugar, high-fat CF diet plays a role in diabetes risk and visceral fat accumulation in people with CF. A total of 30 participants will get a low-added sugar, high-fat diet and the other 30 will get a standard CF diet with no sugar restrictions. Participants will be randomized to the diet group they are assigned. All foods will be provided for 8 weeks.
Primary Outcome
Participants will undergo a Glucose-Potentiated Arginine Stimulation (GPA) Test after a 10-12 hour overnight fast to measure acute insulin (AIRarg) responses during a 230 and 340 mg/dl glucose clamp. This test will measure changes in beta cell secretory capacity.
Conditions Studied
Interventions
- OTHER Low-added sugar, high-fat diet
- OTHER High-added sugar, high-fat CF diet
Study Locations (1)
Georgia
- Emory University Hospital - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-06-28 |
| Est. Completion | 2028-06 |
| Phase | NA |
What NCT05766774 shows while recruiting
NCT05766774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (66% lower).
The record links to 2 conditions, with Cystic Fibrosis appearing as the primary indexed condition, and to 2 interventions - of which Low-added sugar, high-fat diet is the first listed.
NCT05766774 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT05766774 about?
NCT05766774 is a clinical study titled "FEED-Cystic Fibrosis (FEED-CF)". The goal of this study is to determine the extent to which excess dietary sugars serve as a precipitating factor in glucose intolerance in adults with cystic fibrosis (CF), a population at especially high risk for a unique form of diabetes (CF-related diabetes, CFRD) and with standard-of-care dietar...
What is the current status of trial NCT05766774?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-06-28. Estimated completion is 2028-06.
What conditions does trial NCT05766774 study?
This clinical trial studies the following conditions: Cystic Fibrosis, Cystic Fibrosis-related Diabetes.
What interventions are being tested in trial NCT05766774?
The interventions under investigation include: Low-added sugar, high-fat diet (OTHER), High-added sugar, high-fat CF diet (OTHER).
Who is sponsoring clinical trial NCT05766774?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05766774 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cystic Fibrosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05766774's enrollment target sits among peer trials
60 82nd of 169 higher than 86 of 169 other Cystic Fibrosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cystic Fibrosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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