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A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)
NCT05764161 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the safety and tolerability of Ruxolitinib cream in participants with Prurigo Nodularis (PN).
Conditions Studied
Interventions
- DRUG Ruxolitinib Cream
- DRUG Vehicle Cream
Study Locations (20)
New South Wales
- Premier Specialists Pty Ltd — Kogarah
- Liverpool Hospital — Liverpool
- Holdsworth House Medical Practice — Sydney
- Westmead Hospital — Sydney
California
- Dermatology Research Associates — Los Angeles
- Clinical Science Institute Clinical Research Specialists Inc — Santa Monica
- Cura Clinical Research — Sherman Oaks
Ohio
- Oakview Dermatology — Athens
- Aventiv Research Inc-Dublin — Dublin
- Wright State Physicians, Inc. — Fairborn
Pennsylvania
- University of Pittsburgh Medical Center Upmc Dermatology Clinic Oakland Falk Medical Building — Pittsburgh
- Dermdox Center For Dermatology — Sugarloaf
Alabama
- University of Alabama At Birmingham — Birmingham
Arkansas
- Northwest Arkansas Clinical Trials Center — Arkansas City
Florida
- Ars - Maitland Clinical Research Unit — Orlando
Georgia
- Marietta Dermatology the Skin Cancer Center Marietta — Marietta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2023-06-12 |
| Est. Completion | 2025-11-04 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05764161
The ClinicalTrials.gov registry entry for NCT05764161 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 190 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Incyte Corporation, which has 163 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Prurigo Nodularis appearing as the primary indexed condition, and to 2 interventions — of which Ruxolitinib Cream is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05764161 reports 20 study locations spanning 12 distinct geographic areas — top geographies include New South Wales, California, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05764161 about?
NCT05764161 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)". The purpose of this study is to evaluate the safety and tolerability of Ruxolitinib cream in participants with Prurigo Nodularis (PN).
What is the current status of trial NCT05764161?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 190 participants. The study started on 2023-06-12. Estimated completion is 2025-11-04.
What conditions does trial NCT05764161 study?
This clinical trial studies the following conditions: Prurigo Nodularis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05764161?
The interventions under investigation include: Ruxolitinib Cream (DRUG), Vehicle Cream (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05764161?
This trial is sponsored by Incyte Corporation, which has 163 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05764161 being conducted?
This trial has 20 study locations across Alabama, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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