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NCT05757648 · ClinicalTrials.gov registry record · Phase 4
Buffered Local Anesthetic
A Phase 4 study, sponsored by University Hospitals Cleveland Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 20
- Enrollment target
NCT05757648: Completed Phase 4 study, sponsored by University Hospitals Cleveland Medical Center.
NCT05757648 is a Phase 4 study that has completed, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 20 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05757648, a Phase 4 study, has completed, sponsored by University Hospitals Cleveland Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 20 participants
- Enrollment target
Study Summary
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of consciousness). Two types of local anesthetic will be used--one will be buffered (by adding a salt solution to make it less acidic), while the other will be plain, without anything added. Previous studies have shown that the addition of the buffer solution can improve comfort during a dental injection.
Primary Outcome
The BPS score ranges from 2 to 8 points. The higher the score, the more potential pain an unconscious patient is experiencing during sedation procedures.
Interventions
- DRUG Non-buffered Anesthetic
- DRUG Buffered Anesthetic
- DEVICE Onset
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2020-12-08 |
| Est. Completion | 2023-06-12 |
| Phase | Phase 4 |
What the finished NCT05757648 record still lists
NCT05757648 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 3 interventions - of which Non-buffered Anesthetic is the first listed.
NCT05757648 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05757648 about?
NCT05757648 is a clinical study titled "Buffered Local Anesthetic". The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of consciousness). Two types of local anesthetic will be used--one will be buffere...
What is the current status of trial NCT05757648?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2020-12-08. Estimated completion is 2023-06-12.
What interventions are being tested in trial NCT05757648?
The interventions under investigation include: Non-buffered Anesthetic (DRUG), Buffered Anesthetic (DRUG), Onset (DEVICE).
Who is sponsoring clinical trial NCT05757648?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05757648's enrollment target sits among peer trials
20 1753rd of 2000 higher than 167 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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