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NCT05742607 · ClinicalTrials.gov registry record · Phase 2
IPH5201 and Durvalumab in Patients With Resectable Non-Small Cell Lung Cancer (MATISSE)
A Phase 2 study of Non-Small Cell Lung Cancer, sponsored by Innate Pharma.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 70
- Enrollment target
- 20
- Study locations
NCT05742607: Recruiting Phase 2 study of Non-Small Cell Lung Cancer, sponsored by Innate Pharma.
NCT05742607 is a Phase 2 study of Non-Small Cell Lung Cancer that is actively recruiting participants, run by Innate Pharma. The registered enrollment target is 70 participants, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (89% lower). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05742607, a Phase 2 study of Non-Small Cell Lung Cancer, is actively recruiting participants, sponsored by Innate Pharma.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 70 participants
- Enrollment target
- 20
- Study locations
Study Summary
The study is intended to assess the safety and efficacy of neoadjuvant combination of IPH5201 and durvalumab in addition to standard chemotherapy and adjuvant combination of IPH5201 and durvalumab in untreated patients with resectable, early-stage (stage II to IIIA) non-small cell lung cancer (NSCLC).
Primary Outcome
Number of patients with pathological Complete Response (pCR)
Conditions Studied
Interventions
- DRUG IPH5201 + durvalumab + standard chemotherapy
Study Locations (20)
Other
- Angers University Hospital Center - Angers
- University Hospital Center Caen - Caen
- Hospital Calmette - Lille
- CHU de Limoges - Limoges
- Leon Berard Center - Lyon
- Marseille University Hospital Center - North Hospital - Marseille
- Rennes University Hospital Center - Hospital Pontchaillou - Rennes
- Charles Nicolle Hospital - Rouen
- Gustave Roussy - Villejuif
- Henry Dunant Hospital Center - Athens
- University General Hospital "Attikon" - Athens
- University General Hospital of Ioannina - Ioannina
- University General Hospital of Patras - Pátrai
- Koranyi National Institute of Pulmonology, 14th Department of Pulmonology - Budapest
Florida
- St. Anthony's Hospital - BayCare Health System - St. Petersburg
- H. Lee Moffitt Cancer Center & Research Institute - Tampa
Illinois
- University of Chicago Medical Center - Chicago
New York
- Northwell Health Cancer Institute / Center for Novel Cancer Therapeutics - Lake Success
Texas
- Millennium Research & Clinical Development - Houston
Wisconsin
- UW Carbone Cancer Center - Cancer Connect - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2023-06-23 |
| Est. Completion | 2026-09 |
| Phase | Phase 2 |
What NCT05742607 shows while recruiting
NCT05742607 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which IPH5201 + durvalumab + standard chemotherapy is the first listed.
NCT05742607 names 20 study sites across 6 states, led by Other, Florida, Illinois.
Frequently Asked Questions
What is clinical trial NCT05742607 about?
NCT05742607 is a clinical study titled "IPH5201 and Durvalumab in Patients With Resectable Non-Small Cell Lung Cancer (MATISSE)". The study is intended to assess the safety and efficacy of neoadjuvant combination of IPH5201 and durvalumab in addition to standard chemotherapy and adjuvant combination of IPH5201 and durvalumab in untreated patients with resectable, early-stage (stage II to IIIA) non-small cell lung cancer (NSCLC...
What is the current status of trial NCT05742607?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2023-06-23. Estimated completion is 2026-09.
What conditions does trial NCT05742607 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer.
What interventions are being tested in trial NCT05742607?
The interventions under investigation include: IPH5201 + durvalumab + standard chemotherapy (DRUG).
Who is sponsoring clinical trial NCT05742607?
This trial is sponsored by Innate Pharma, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05742607 being conducted?
This trial has 20 study locations across Florida, Illinois, New York, Texas, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Non-Small Cell Lung Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05742607's enrollment target sits among peer trials
70 289th of 454 higher than 161 of 454 other Non-Small Cell Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Small Cell Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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