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NCT05730725 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe Psoriasis

A Phase 2 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 2
Development phase
109
Enrollment target

NCT05730725: Completed Phase 2 study, sponsored by Bristol-Myers Squibb.

NCT05730725 is a Phase 2 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 109 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (18% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05730725, a Phase 2 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 2
Development phase
109 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate clinical effectiveness and safety of BMS-986322 in participants with moderate-to-severe psoriasis.

Primary Outcome

PASI is a measure of the average erythema, induration thickness, and scaling of psoriatic skin lesions (each graded on a 0 to 4 scale), weighted by the area of involvement (head, arms, trunk to groin, and legs to top of buttocks). The PASI produces a numeric score that can range from 0 to 72, with higher PASI scores denoting more severe disease activity. The PASI-75 response rate is defined as the percentage of participants with moderate-to-severe PsO achieving at least 75% reduction from base

Interventions

  • OTHER Placebo
  • DRUG BMS-986322

Trial Details

FieldValue
Enrollment Target 109 participants
Start Date 2023-04-03
Est. Completion 2024-08-06
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

What the finished NCT05730725 record still lists

NCT05730725 is an interventional study that assigns participants to a tested intervention. The registered 109 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (18% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05730725 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05730725 about?

NCT05730725 is a clinical study titled "A Study to Evaluate Effectiveness and Safety of BMS-986322 in Participants With Moderate-to-Severe Psoriasis". The purpose of this study is to evaluate clinical effectiveness and safety of BMS-986322 in participants with moderate-to-severe psoriasis.

What is the current status of trial NCT05730725?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 109 participants. The study started on 2023-04-03. Estimated completion is 2024-08-06.

What interventions are being tested in trial NCT05730725?

The interventions under investigation include: Placebo (OTHER), BMS-986322 (DRUG).

Who is sponsoring clinical trial NCT05730725?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05730725's enrollment target sits among peer trials

109 640th of 2000 higher than 1,361 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05730725, the US trial registry maintained by the National Library of Medicine. NCT05730725 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.