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NCT05726279 · ClinicalTrials.gov registry record · NA

PROtecting Maternal Brains From Injury and Stroke

A NA study, sponsored by Columbia University.

Terminated
Registry status
NA
Development phase
26
Enrollment target

NCT05726279: Clinical Trial NA study, sponsored by Columbia University.

NCT05726279 is a NA study that was terminated before completion, run by Columbia University. The registered enrollment target is 26 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05726279, a NA study, was terminated before completion, sponsored by Columbia University.

TERMINATED
Registry status
NA
Development phase
26 participants
Enrollment target

Study Summary

The purpose of this study is to test a new approach to blood pressure management in postpartum preeclampsia. There will be two groups of patients in this early stage single center trial. Both groups of study participants (observational and interventional) will be treated with standard blood pressure medications while undergoing continuous non-invasive blood pressure and near infrared spectroscopy (NIRS) monitoring for 24 hours. The interventional group will have personalized blood pressure targets according to results of NIRS monitoring which will be updated in real time.

Primary Outcome

The total time (in minutes) each participant had their mean arterial blood pressure (MAP) values within their computed limits of autoregulation will be measured. The primary outcome is the percentage of time the MAP is outside the personalized limits of autoregulation.

Interventions

  • DEVICE NIRS based personalized blood pressure management

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2023-05-04
Est. Completion 2025-02-28
Phase NA
Columbia University

958 total trials

Why NCT05726279 stopped before completion

NCT05726279 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which NIRS based personalized blood pressure management is the first listed.

NCT05726279 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05726279 about?

NCT05726279 is a clinical study titled "PROtecting Maternal Brains From Injury and Stroke". The purpose of this study is to test a new approach to blood pressure management in postpartum preeclampsia. There will be two groups of patients in this early stage single center trial. Both groups of study participants (observational and interventional) will be treated with standard blood pressure...

What is the current status of trial NCT05726279?

This trial is currently terminated. It is a NA study. The enrollment target is 26 participants. The study started on 2023-05-04. Estimated completion is 2025-02-28.

What interventions are being tested in trial NCT05726279?

The interventions under investigation include: NIRS based personalized blood pressure management (DEVICE).

Who is sponsoring clinical trial NCT05726279?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05726279's enrollment target sits among peer trials

26 1710th of 2000 higher than 289 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05726279, the US trial registry maintained by the National Library of Medicine. NCT05726279 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.