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NCT05722860 · ClinicalTrials.gov registry record · Phase 1
L-Citrulline and Endothelial Function
A Phase 1 study, sponsored by University of Oklahoma.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT05722860: Completed Phase 1 study, sponsored by University of Oklahoma.
NCT05722860 is a Phase 1 study that has completed, run by University of Oklahoma. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05722860, a Phase 1 study, has completed, sponsored by University of Oklahoma.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The effect of L-Citrulline is well studied in relation to muscle strength, exhaustion, exercise performance, and endothelial function in health and disease. This study will extend current body of knowledge and will investigate the effect of L-Citrulline on brain vascular function.
Primary Outcome
Functional near infrared spectroscopy (fNIRS) will be performed during the cognitive n-back task. fNIRS approach generates data that represent a relative change in oxygenated and deoxygenated hemoglobin measured over the cortical brain tissues. Neurovascular coupling will be evaluated as a change in oxy- and deoxy-hemoglobin between before and after treatment. Units of measure - beta. Reported as a %change from baseline, before and after treatment.
Interventions
- DRUG L-Citrulline, capsule
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-01-03 |
| Est. Completion | 2024-12-28 |
| Phase | Phase 1 |
What the finished NCT05722860 record still lists
NCT05722860 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 1 intervention - of which L-Citrulline, capsule is the first listed.
NCT05722860 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05722860 about?
NCT05722860 is a clinical study titled "L-Citrulline and Endothelial Function". The effect of L-Citrulline is well studied in relation to muscle strength, exhaustion, exercise performance, and endothelial function in health and disease. This study will extend current body of knowledge and will investigate the effect of L-Citrulline on brain vascular function.
What is the current status of trial NCT05722860?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2024-01-03. Estimated completion is 2024-12-28.
What interventions are being tested in trial NCT05722860?
The interventions under investigation include: L-Citrulline, capsule (DRUG).
Who is sponsoring clinical trial NCT05722860?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05722860's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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