Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 2

A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors

NCT05712356 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical trial is to test a new drug plus standard treatment compared with standard treatment alone in patients with previously untreated cholangiocarcinoma or those that have progressed after first-line treatment for cholangiocarcinoma. The main questions it aims to answer are: * is the new drug plus standard treatment safe and tolerable * is the new drug plus standard treatment more effective than standard treatment

Interventions

  • DRUG Cisplatin
  • DRUG Gemcitabine
  • DRUG FOLFOX regimen
  • DRUG Durvalumab
  • DRUG certepetide

Study Locations (19)

Arizona

  • Banner MD Anderson Cancer Center — Gilbert
  • Mayo Clinic Arizona — Phoenix
  • University of Arizona Cancer Center — Tucson

Kentucky

  • University of Kentucky Medical Center — Lexington
  • Norton Cancer Institute, Downtown — Louisville
  • Norton Cancer Institute, Audubon — Louisville

Kansas

  • Alliance for Multispecialty Research — Merriam
  • University of Kansas Cancer Center — Westwood

New York

  • Northwell Health - Zuckerberg Cancer Center — Lake Success
  • Stony Brook Cancer Center — Stony Brook

Texas

  • University of Texas Southwestern Medical Center — Dallas
  • The University of Texas MD Anderson Cancer Center — Houston

Florida

  • Moffitt Cancer Center — Tampa

Minnesota

  • Mayo Clinic Rochester — Rochester

North Carolina

  • FirstHealth of the Carolinas, Inc. — Pinehurst

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2023-08-24
Est. Completion 2030-03
Phase Phase 2

Sponsor

Lisata Therapeutics

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05712356

The ClinicalTrials.gov registry entry for NCT05712356 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Lisata Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 8 conditions, with Cholangiocarcinoma appearing as the primary indexed condition, and to 5 interventions — of which Cisplatin is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05712356 reports 19 study locations spanning 12 distinct geographic areas — top geographies include Arizona, Kentucky, Kansas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05712356 about?

NCT05712356 is a clinical study titled "A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid Tumors". The goal of this clinical trial is to test a new drug plus standard treatment compared with standard treatment alone in patients with previously untreated cholangiocarcinoma or those that have progressed after first-line treatment for cholangiocarcinoma. The main questions it aims to answer are: *...

What is the current status of trial NCT05712356?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 67 participants. The study started on 2023-08-24. Estimated completion is 2030-03.

What conditions does trial NCT05712356 study?

This clinical trial studies the following conditions: Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma, Bile Duct Cancer, Gallbladder Cancer, Gallbladder Carcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05712356?

The interventions under investigation include: Cisplatin (DRUG), Gemcitabine (DRUG), FOLFOX regimen (DRUG), Durvalumab (DRUG), certepetide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05712356?

This trial is sponsored by Lisata Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05712356 being conducted?

This trial has 19 study locations across Arizona, Florida, Kansas, Kentucky, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial