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NCT05708976 · ClinicalTrials.gov registry record · NA

HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2

A NA study, sponsored by University of California, San Francisco.

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT05708976: Completed NA study, sponsored by University of California, San Francisco.

NCT05708976 is a NA study that has completed, run by University of California, San Francisco. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05708976, a NA study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

This randomized two-arm intervention trial administers 8 weekly cognitive behavioral therapy (CBT) sessions and 4 bi-weekly active whole-body hyperthermia (active WBH) sessions or 4 bi-weekly sham WBH sessions to adults aged 18 years or older with major depressive disorder (MDD).

Primary Outcome

Study acceptability was indexed by participant-reported net-promoter scores. This is a response to a single question: "How likely would you be to recommend \[participation in a study or treatment like this\] to a friend or family member with depression?" Net promoter scores range from 0 (would not recommend) to 10 (would definitely recommend). Study acceptability was also indexed by an additional patient-reported metric, Enrollment Likelihood. Enrollment likelihood was a response to the question

Interventions

  • BEHAVIORAL Cognitive Behavioral Therapy (CBT)
  • DEVICE Active Whole-Body Hyperthermia (Active WBH)
  • DEVICE Sham Whole-Body Hyperthermia (Sham WBH)

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2023-02-15
Est. Completion 2024-09-30
Phase NA

What the finished NCT05708976 record still lists

NCT05708976 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 3 interventions - of which Cognitive Behavioral Therapy (CBT) is the first listed.

NCT05708976 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05708976 about?

NCT05708976 is a clinical study titled "HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2". This randomized two-arm intervention trial administers 8 weekly cognitive behavioral therapy (CBT) sessions and 4 bi-weekly active whole-body hyperthermia (active WBH) sessions or 4 bi-weekly sham WBH sessions to adults aged 18 years or older with major depressive disorder (MDD).

What is the current status of trial NCT05708976?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2023-02-15. Estimated completion is 2024-09-30.

What interventions are being tested in trial NCT05708976?

The interventions under investigation include: Cognitive Behavioral Therapy (CBT) (BEHAVIORAL), Active Whole-Body Hyperthermia (Active WBH) (DEVICE), Sham Whole-Body Hyperthermia (Sham WBH) (DEVICE).

Who is sponsoring clinical trial NCT05708976?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05708976's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05708976, the US trial registry maintained by the National Library of Medicine. NCT05708976 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.