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NCT05704556 · ClinicalTrials.gov registry record · Phase 1

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal Impairment

A Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.

Completed
Registry status
Phase 1
Development phase
38
Enrollment target

NCT05704556 is a Phase 1 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 38 participants.

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The verdict

NCT05704556, a Phase 1 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.

COMPLETED
Registry status
Phase 1
Development phase
38 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the pharmacokinetics (PK), safety, and tolerability of VX-548 and its metabolite in participants with severe or moderate renal impairment and healthy participants.

Interventions

  • DRUG VX-548

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2023-02-27
Est. Completion 2024-03-30
Phase Phase 1

Sponsor

Vertex Pharmaceuticals Incorporated

191 total trials

What the Registry Record Tells You About NCT05704556

The ClinicalTrials.gov registry entry for NCT05704556 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which VX-548 is the first listed.

NCT05704556 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05704556 about?

NCT05704556 is a clinical study titled "Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Renal Impairment". The purpose of this study is to evaluate the pharmacokinetics (PK), safety, and tolerability of VX-548 and its metabolite in participants with severe or moderate renal impairment and healthy participants.

What is the current status of trial NCT05704556?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 38 participants. The study started on 2023-02-27. Estimated completion is 2024-03-30.

What interventions are being tested in trial NCT05704556?

The interventions under investigation include: VX-548 (DRUG).

Who is sponsoring clinical trial NCT05704556?

This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.