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NCT05700227 · ClinicalTrials.gov registry record · NA

Daily Online Adaptive Short-Course Radiation Therapy and Concurrent Chemotherapy for Muscle-Invasive Bladder Cancer

A NA study, sponsored by Varian, a Siemens Healthineers Company.

Terminated
Registry status
NA
Development phase
2
Enrollment target

NCT05700227: Clinical Trial NA study, sponsored by Varian, a Siemens Healthineers Company.

NCT05700227 is a NA study that was terminated before completion, run by Varian, a Siemens Healthineers Company. The registered enrollment target is 2 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05700227, a NA study, was terminated before completion, sponsored by Varian, a Siemens Healthineers Company.

TERMINATED
Registry status
NA
Development phase
2 participants
Enrollment target

Study Summary

This trial is a single-arm, prospective, multi-center clinical trial designed to demonstrate that adaptive radiotherapy for muscle-invasive bladder cancer will translate into a decreased rate of acute (assessed weekly during chemo-radiotherapy) grade 3 or greater gastrointestinal/genitourinary toxicity compared with the historically reported rate for non-adaptive radiation therapy. The Common Terminology Criteria for Adverse Events (CTCAE) version 5 assessment tool will be utilized.

Primary Outcome

Acute gastrointestinal and genitourinary CTCAE v5 grade 3 or higher toxicity

Interventions

  • RADIATION Daily Adaptive External Beam Radiation Therapy

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2023-02-02
Est. Completion 2024-05-09
Phase NA

Why NCT05700227 stopped before completion

NCT05700227 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 1 intervention - of which Daily Adaptive External Beam Radiation Therapy is the first listed.

NCT05700227 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05700227 about?

NCT05700227 is a clinical study titled "Daily Online Adaptive Short-Course Radiation Therapy and Concurrent Chemotherapy for Muscle-Invasive Bladder Cancer". This trial is a single-arm, prospective, multi-center clinical trial designed to demonstrate that adaptive radiotherapy for muscle-invasive bladder cancer will translate into a decreased rate of acute (assessed weekly during chemo-radiotherapy) grade 3 or greater gastrointestinal/genitourinary toxic...

What is the current status of trial NCT05700227?

This trial is currently terminated. It is a NA study. The enrollment target is 2 participants. The study started on 2023-02-02. Estimated completion is 2024-05-09.

What interventions are being tested in trial NCT05700227?

The interventions under investigation include: Daily Adaptive External Beam Radiation Therapy (RADIATION).

Who is sponsoring clinical trial NCT05700227?

This trial is sponsored by Varian, a Siemens Healthineers Company, which has 16 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05700227's enrollment target sits among peer trials

2 1997th of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05700227, the US trial registry maintained by the National Library of Medicine. NCT05700227 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.