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NCT05685407 · ClinicalTrials.gov registry record · Phase 1
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
A Phase 1 study of Female Sexual Arousal Disorder, sponsored by University of Texas at Austin.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05685407 is a Phase 1 study of Female Sexual Arousal Disorder that has completed, run by University of Texas at Austin. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state.
The verdict
NCT05685407, a Phase 1 study of Female Sexual Arousal Disorder, has completed, sponsored by University of Texas at Austin.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence. Moderate sympathetic nervous system (SNS) activation through exercise has shown promising results for improving antidepressant-induced genital arousal dysfunction. It is feasible that caffeine - an SNS stimulant - could improve antidepressant-induced genital arousal difficulties if ingested prior to sex. The goal of the present pilot study is to examine whether the acute administration of 300mg of caffeine increases genital arousal in women experiencing antidepressant-induced genital arousal difficulties. Women will attend two counterbalanced sessions in which they ingest either 300mg caffeine or placebo. Fifteen minutes after ingestion, they will view an erotic film while their heart rate and genital sexual arousal are measured. Caffeine could serve as a low-cost, widely accessible intervention with minimal side effects if efficacy is shown.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Caffeine
Study Locations (1)
Texas
- The University of Texas at Austin, Sexual Psychophysiology Laboratory - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2023-01-01 |
| Est. Completion | 2023-04-15 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05685407
The ClinicalTrials.gov registry entry for NCT05685407 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Texas at Austin, which has 257 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Female Sexual Arousal Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05685407 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT05685407 about?
NCT05685407 is a clinical study titled "Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women". Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence. Moderate sympathetic nervous system (SNS) activation through exercise has shown promising results for improving antidepressant-induced genital arousal dysfunction. It is...
What is the current status of trial NCT05685407?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2023-01-01. Estimated completion is 2023-04-15.
What conditions does trial NCT05685407 study?
This clinical trial studies the following conditions: Female Sexual Arousal Disorder.
What interventions are being tested in trial NCT05685407?
The interventions under investigation include: Placebo (OTHER), Caffeine (DRUG).
Who is sponsoring clinical trial NCT05685407?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05685407 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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