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NCT05672771 · ClinicalTrials.gov registry record · NA
The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults
A NA study, sponsored by University of Illinois at Urbana-Champaign.
- Completed
- Registry status
- NA
- Development phase
- 90
- Enrollment target
NCT05672771: Completed NA study, sponsored by University of Illinois at Urbana-Champaign.
NCT05672771 is a NA study that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 90 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05672771, a NA study, has completed, sponsored by University of Illinois at Urbana-Champaign.
- COMPLETED
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
Study Summary
While an intellectually active and socially integrated lifestyle shows promise for promoting cognitive resilience, the mechanisms underlying any such effects are not well understood. The aim of the current project is test the implications of the "mutualism" hypothesis, which suggests that intellectual function emerges out of the reciprocal influence of growth in abilities as they are exercised in the ecology of everyday life. Such a view implies that improvement in one component will enhance the modifiability of a related component. An additional aim was to test the idea that mutualistic effects will be enhanced by more diverse training in related skills, such as interleaved training of multiple skills, relative to single-component training. A "successive-enrichment" paradigm was developed to test this with working memory (WM) as the target for training given its centrality in models of attention, intellectual function, and everyday capacities such as reasoning and language comprehension. All participants receive the same target training, but the nature of the training that precedes it is manipulated. Outcome measures include pre- to posttest gains in working memory and episodic memory, as well as the rate of gain in learning the target task. The principle of enhanced mutualism would predict that more diverse experiences related to the target skill will enhance efficiency in acquiring the target skill.
Primary Outcome
Average change in working memory from pre- to posttest in z-score units ("standard unit change"). For each working memory measure (Reading Span, Lexical Decision Span, Category Span, Operation Span, and Count Span), the change in z-score units was calculated \[(posttest score - pretest score) / standard deviation of the scores at pretest)\]. The score reported is the mean of these 5 values. A z-score of 0 represents no change from pretest to posttest; the unit is the standard deviations of the s
Interventions
- BEHAVIORAL Different Mixed Condition (DM)
- BEHAVIORAL Different Single Condition (DS)
- BEHAVIORAL Same Task (ST) Practice Control
- BEHAVIORAL Non-WM Placebo Control (PC)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2020-08-26 |
| Est. Completion | 2022-01-30 |
| Phase | NA |
What the finished NCT05672771 record still lists
NCT05672771 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 4 interventions - of which Different Mixed Condition (DM) is the first listed.
NCT05672771 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05672771 about?
NCT05672771 is a clinical study titled "The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults". While an intellectually active and socially integrated lifestyle shows promise for promoting cognitive resilience, the mechanisms underlying any such effects are not well understood. The aim of the current project is test the implications of the "mutualism" hypothesis, which suggests that intellectu...
What is the current status of trial NCT05672771?
This trial is currently completed. It is a NA study. The enrollment target is 90 participants. The study started on 2020-08-26. Estimated completion is 2022-01-30.
What interventions are being tested in trial NCT05672771?
The interventions under investigation include: Different Mixed Condition (DM) (BEHAVIORAL), Different Single Condition (DS) (BEHAVIORAL), Same Task (ST) Practice Control (BEHAVIORAL), Non-WM Placebo Control (PC) (BEHAVIORAL).
Who is sponsoring clinical trial NCT05672771?
This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05672771's enrollment target sits among peer trials
90 941st of 2000 higher than 1,029 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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