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NCT05667324 · ClinicalTrials.gov registry record · Phase 4
Septorhinoplasty Post-operative Pain Control With SPG Nerve Block
A Phase 4 study of Deviated Nasal Septum, sponsored by University of Florida.
- Completed
- Registry status
- Phase 4
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05667324: Completed Phase 4 study of Deviated Nasal Septum, sponsored by University of Florida.
NCT05667324 is a Phase 4 study of Deviated Nasal Septum that has completed, run by University of Florida. The registered enrollment target is 50 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05667324, a Phase 4 study of Deviated Nasal Septum, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Maxillary nerve blocks have been shown to significantly reduce post-operative pain and analgesic intake during the 24-hour period following sinus surgery. This randomized, double-blinded, placebo-controlled study will investigate blocks of the pterygopalatine fossa using a suprazygomatic approach during septorhinoplasty surgery. It is the investigator's hypothesis that this technique will result in decreased post-operative pain and opioid use, and the morbidity associated with it.
Primary Outcome
To assess if bilateral sphenopalatine nerve blocks can decrease post operative pain scores on a scale from 0-10, with a 0 meaning no pain and 10 meaning extreme pain. Pain scores were assessed on post operative days 1, 3 and 5.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Dexamethasone
- DRUG Ropivacaine
Study Locations (1)
Florida
- UF Health of University of Florida - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-04-12 |
| Est. Completion | 2025-02-28 |
| Phase | Phase 4 |
What the finished NCT05667324 record still lists
NCT05667324 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Deviated Nasal Septum appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT05667324 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT05667324 about?
NCT05667324 is a clinical study titled "Septorhinoplasty Post-operative Pain Control With SPG Nerve Block". Maxillary nerve blocks have been shown to significantly reduce post-operative pain and analgesic intake during the 24-hour period following sinus surgery. This randomized, double-blinded, placebo-controlled study will investigate blocks of the pterygopalatine fossa using a suprazygomatic approach du...
What is the current status of trial NCT05667324?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2023-04-12. Estimated completion is 2025-02-28.
What conditions does trial NCT05667324 study?
This clinical trial studies the following conditions: Deviated Nasal Septum.
What interventions are being tested in trial NCT05667324?
The interventions under investigation include: Placebo (DRUG), Dexamethasone (DRUG), Ropivacaine (DRUG).
Who is sponsoring clinical trial NCT05667324?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05667324 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05667324's enrollment target sits among peer trials
50 1255th of 2000 higher than 679 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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