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NCT05664672 · ClinicalTrials.gov registry record · NA
Study to Evaluate Changes in Smokers Using on!® Nicotine Pouches
A NA study, sponsored by Altria Client Services.
- Completed
- Registry status
- NA
- Development phase
- 149
- Enrollment target
NCT05664672: Completed NA study, sponsored by Altria Client Services.
NCT05664672 is a NA study that has completed, run by Altria Client Services. The registered enrollment target is 149 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05664672, a NA study, has completed, sponsored by Altria Client Services.
- COMPLETED
- Registry status
- NA
- Development phase
- 149 participants
- Enrollment target
Study Summary
The purpose of this study is to generate evidence regarding the extent of reduction in exposure to selected HPHCs in adult smokers switching to on!® NPs. The study intends to determine changes in exposure to selected HPHCs by measuring biomarkers in adult smokers who completely switch from smoking to use of on!® NP compared to those who continue smoking cigarettes or stop using all tobacco products.
Primary Outcome
Summary of 24-hour urinary creatinine-adjusted total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in subjects using nicotine pouches (NP) for 7 days versus subjects who continue to smoke cigarettes for 7 days and subjects who stopped using any tobacco products for 7 days. Total urine weight (g) collected during 24 hours was converted to 24-hour urine volume using assumed density of 1 g = 1 mL Amount of biomarker was calculated as: Urine Biomarker (unit2/24 hours) = Urine biomarker con
Interventions
- OTHER OTDN Product 1
- OTHER OTDN Product 2
- OTHER OTDN Product 3
- OTHER No Tobacco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 149 participants |
| Start Date | 2021-05-11 |
| Est. Completion | 2021-08-31 |
| Phase | NA |
What the finished NCT05664672 record still lists
NCT05664672 is an interventional study that assigns participants to a tested intervention. The registered 149 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 4 interventions - of which OTDN Product 1 is the first listed.
NCT05664672 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05664672 about?
NCT05664672 is a clinical study titled "Study to Evaluate Changes in Smokers Using on!® Nicotine Pouches". The purpose of this study is to generate evidence regarding the extent of reduction in exposure to selected HPHCs in adult smokers switching to on!® NPs. The study intends to determine changes in exposure to selected HPHCs by measuring biomarkers in adult smokers who completely switch from smoking t...
What is the current status of trial NCT05664672?
This trial is currently completed. It is a NA study. The enrollment target is 149 participants. The study started on 2021-05-11. Estimated completion is 2021-08-31.
What interventions are being tested in trial NCT05664672?
The interventions under investigation include: OTDN Product 1 (OTHER), OTDN Product 2 (OTHER), OTDN Product 3 (OTHER), No Tobacco (OTHER).
Who is sponsoring clinical trial NCT05664672?
This trial is sponsored by Altria Client Services, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05664672's enrollment target sits among peer trials
149 702nd of 2000 higher than 1,299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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