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NCT05664100 · ClinicalTrials.gov registry record · Phase 1

First in Human Safety Study of FX-345 in Adults With Sensorineural Hearing Loss

A Phase 1 study, sponsored by Frequency Therapeutics.

Terminated
Registry status
Phase 1
Development phase
6
Enrollment target

NCT05664100 is a Phase 1 study that was terminated before completion, run by Frequency Therapeutics. The registered enrollment target is 6 participants.

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The verdict

NCT05664100, a Phase 1 study, was terminated before completion, sponsored by Frequency Therapeutics.

TERMINATED
Registry status
Phase 1
Development phase
6 participants
Enrollment target

Study Summary

This single-blind, placebo-controlled trial will be conducted to evaluate the safety of FX-345 administered as a single intratympanic injection in adults with acquired sensorineural hearing loss. The primary objectives are to assess the local safety, systemic safety, and pharmacokinetic (PK) profile to determine systemic exposure.

Interventions

  • DRUG Placebo
  • DRUG FX-345

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2022-12-15
Est. Completion 2023-04-12
Phase Phase 1

Sponsor

Frequency Therapeutics

6 total trials

What the Registry Record Tells You About NCT05664100

The ClinicalTrials.gov registry entry for NCT05664100 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Frequency Therapeutics, which has 6 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05664100 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05664100 about?

NCT05664100 is a clinical study titled "First in Human Safety Study of FX-345 in Adults With Sensorineural Hearing Loss". This single-blind, placebo-controlled trial will be conducted to evaluate the safety of FX-345 administered as a single intratympanic injection in adults with acquired sensorineural hearing loss. The primary objectives are to assess the local safety, systemic safety, and pharmacokinetic (PK) profile...

What is the current status of trial NCT05664100?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2022-12-15. Estimated completion is 2023-04-12.

What interventions are being tested in trial NCT05664100?

The interventions under investigation include: Placebo (DRUG), FX-345 (DRUG).

Who is sponsoring clinical trial NCT05664100?

This trial is sponsored by Frequency Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.