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NCT05659264 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure
A Phase 1 study, sponsored by ModernaTX.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT05659264: Completed Phase 1 study, sponsored by ModernaTX.
NCT05659264 is a Phase 1 study that has completed, run by ModernaTX. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05659264, a Phase 1 study, has completed, sponsored by ModernaTX.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
The primary objective of this study is to evaluate the safety and tolerability of single and multiple doses at escalating dose levels of mRNA-0184.
Interventions
- DRUG Placebo
- DRUG mRNA-0184
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2022-12-05 |
| Est. Completion | 2024-12-17 |
| Phase | Phase 1 |
What the finished NCT05659264 record still lists
NCT05659264 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05659264 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05659264 about?
NCT05659264 is a clinical study titled "A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure". The primary objective of this study is to evaluate the safety and tolerability of single and multiple doses at escalating dose levels of mRNA-0184.
What is the current status of trial NCT05659264?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2022-12-05. Estimated completion is 2024-12-17.
What interventions are being tested in trial NCT05659264?
The interventions under investigation include: Placebo (DRUG), mRNA-0184 (DRUG).
Who is sponsoring clinical trial NCT05659264?
This trial is sponsored by ModernaTX, which has 90 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05659264's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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