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NCT05658861 · ClinicalTrials.gov registry record · NA
Comparing the Gastric Transit of Commercial Milk and A2 Milk
A NA study, sponsored by Purdue University.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT05658861: Completed NA study, sponsored by Purdue University.
NCT05658861 is a NA study that has completed, run by Purdue University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05658861, a NA study, has completed, sponsored by Purdue University.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Cow's milk contains two types of β-casein: A1 and A2. The μ-opioid peptide BCM-7 is released from A1 but not from A2. BCM-7 is associated with slower gastrointestinal transit and hence increased gastrointestinal transit times. Lactose maldigesters reported an increase in abdominal pain due to consumption of milk containing A1 beta-casein as compared to milk containing only A2 beta-casein. The hypothesis of this study is that the differential abdominal pain is due to the differential gastric transit. This is a double-blinded, randomized, controlled trial conducted to determine if the transit of A1 β-casein milk is modified in the stomach as compared to milk with only A2 β-casein.
Primary Outcome
Volume of milk in the stomach will be calculated using FSL software with MRI images acquired at 0, 10, 30, 60 and 120 minutes.
Interventions
- OTHER Milk containing A1 and A2 beta-casein
- OTHER Milk containing only A2 beta-casein
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2021-06-21 |
| Est. Completion | 2022-12-01 |
| Phase | NA |
What the finished NCT05658861 record still lists
NCT05658861 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Milk containing A1 and A2 beta-casein is the first listed.
NCT05658861 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05658861 about?
NCT05658861 is a clinical study titled "Comparing the Gastric Transit of Commercial Milk and A2 Milk". Cow's milk contains two types of β-casein: A1 and A2. The μ-opioid peptide BCM-7 is released from A1 but not from A2. BCM-7 is associated with slower gastrointestinal transit and hence increased gastrointestinal transit times. Lactose maldigesters reported an increase in abdominal pain due to consum...
What is the current status of trial NCT05658861?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2021-06-21. Estimated completion is 2022-12-01.
What interventions are being tested in trial NCT05658861?
The interventions under investigation include: Milk containing A1 and A2 beta-casein (OTHER), Milk containing only A2 beta-casein (OTHER).
Who is sponsoring clinical trial NCT05658861?
This trial is sponsored by Purdue University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05658861's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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