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NCT05650567 · ClinicalTrials.gov registry record · Phase 2
Study of M5049 in DM and PM Participants (NEPTUNIA)
A Phase 2 study, sponsored by EMD Serono Research & Development Institute.
- Terminated
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT05650567: Clinical Trial Phase 2 study, sponsored by EMD Serono Research & Development Institute.
NCT05650567 is a Phase 2 study that was terminated before completion, run by EMD Serono Research & Development Institute. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05650567, a Phase 2 study, was terminated before completion, sponsored by EMD Serono Research & Development Institute.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the efficacy and safety of orally administered M5049 in idiopathic inflammatory myopathies, specifically dermatomyositis (DM) and polymyositis (PM) participants for 24 weeks.
Interventions
- DRUG Placebo
- DRUG M5049 high dose
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-01-19 |
| Est. Completion | 2025-06-25 |
| Phase | Phase 2 |
Why NCT05650567 stopped before completion
NCT05650567 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05650567 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05650567 about?
NCT05650567 is a clinical study titled "Study of M5049 in DM and PM Participants (NEPTUNIA)". The purpose of this study is to evaluate the efficacy and safety of orally administered M5049 in idiopathic inflammatory myopathies, specifically dermatomyositis (DM) and polymyositis (PM) participants for 24 weeks.
What is the current status of trial NCT05650567?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2023-01-19. Estimated completion is 2025-06-25.
What interventions are being tested in trial NCT05650567?
The interventions under investigation include: Placebo (DRUG), M5049 high dose (DRUG).
Who is sponsoring clinical trial NCT05650567?
This trial is sponsored by EMD Serono Research & Development Institute, which has 81 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05650567's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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