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NCT05643716 · ClinicalTrials.gov registry record · NA
The Effects of Exercise on Emotion Regulation and Cognitive Control in PTSD
A NA study, sponsored by Michigan State University.
- Completed
- Registry status
- NA
- Development phase
- 67
- Enrollment target
NCT05643716: Completed NA study, sponsored by Michigan State University.
NCT05643716 is a NA study that has completed, run by Michigan State University. The registered enrollment target is 67 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05643716, a NA study, has completed, sponsored by Michigan State University.
- COMPLETED
- Registry status
- NA
- Development phase
- 67 participants
- Enrollment target
Study Summary
The goal of this study is to investigate the effects of a single bout of aerobic exercise on neurophysiological indices of emotion regulation and cognitive control in individuals with clinically significant PTSD symptoms. In this proposed study, 65 adult females with clinically significant PTSD symptoms will be randomized into two groups: a 20-minute moderate-to-vigorous intensity aerobic exercise group, or a 20-minute silent sitting control group. Prior to and following the exercise/sitting session, participants will complete a letter flanker task and an emotion regulation picture viewing task while their electrical brain activity is continuously recorded via electroencephalogram (EEG). Utilizing a multimodal assessment approach, cognitive control will be measured using behavioral (i.e., accuracy, reaction time) and neurophysiology (i.e., P300, error-related negativity; ERN). Emotion regulation will be measured using self-reported and neurophysiological indices of emotional reactivity (i.e., late positive potential; LPP).
Primary Outcome
Participants will be presented with a series of negative high arousing and neutral low-arousing images from the International Affective Picture System. Prior to being presented with each image, participants will be cued to either passively view the upcoming image or to use reappraisal to "reinterpret aspects of the upcoming image in order to adopt a more neutral or positive perspective." During the emotion regulation task, "online" emotional arousal during reappraisal and passive view trials wil
Interventions
- BEHAVIORAL Aerobic Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 67 participants |
| Start Date | 2024-03-05 |
| Est. Completion | 2025-03-01 |
| Phase | NA |
What the finished NCT05643716 record still lists
NCT05643716 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 67 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 1 intervention - of which Aerobic Exercise is the first listed.
NCT05643716 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05643716 about?
NCT05643716 is a clinical study titled "The Effects of Exercise on Emotion Regulation and Cognitive Control in PTSD". The goal of this study is to investigate the effects of a single bout of aerobic exercise on neurophysiological indices of emotion regulation and cognitive control in individuals with clinically significant PTSD symptoms. In this proposed study, 65 adult females with clinically significant PTSD symp...
What is the current status of trial NCT05643716?
This trial is currently completed. It is a NA study. The enrollment target is 67 participants. The study started on 2024-03-05. Estimated completion is 2025-03-01.
What interventions are being tested in trial NCT05643716?
The interventions under investigation include: Aerobic Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT05643716?
This trial is sponsored by Michigan State University, which has 120 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05643716's enrollment target sits among peer trials
67 1139th of 2000 higher than 862 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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