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NCT05634733 · ClinicalTrials.gov registry record
Change in MAPSE During Treatment of Sepsis
A clinical trial of Sepsis, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT05634733: Recruiting study of Sepsis, sponsored by University of Maryland, Baltimore.
NCT05634733 is a study of Sepsis that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 50 participants, below the 6,564-participant average among 90 other Sepsis trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05634733, a study of Sepsis, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the form of low blood pressure (shock) and heart failure. Ultrasound is frequently used in the emergency department to evaluate why a patient might have low blood pressure. Part of that evaluation may include obtaining ultrasound images and making measurements about how well or poorly the heart is pumping. The investigators will evaluate a certain measurement that relates to cardiac function, determine how it changes in patients before and after they are treated for septic shock. This will involve placing an ultrasound probe on the patient's chest, measuring the upward and downward movement of the mitral valve, the mitral annulus systolic plane excursion (MAPSE), and comparing the measurements before and after treatment is started. The investigators are attempting to determine if this measurement improves before and after treatment.
Primary Outcome
Does the MAPSE change after treatment of MAPSE
Conditions Studied
Interventions
- OTHER Treatment of Sepsis
Study Locations (1)
Maryland
- University of Maryland Medical Center - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2030-12-01 |
What NCT05634733 shows while recruiting
NCT05634733 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 6,564-participant average among 90 other Sepsis trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Sepsis appearing as the primary indexed condition, and to 1 intervention - of which Treatment of Sepsis is the first listed.
NCT05634733 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05634733 about?
NCT05634733 is a clinical study titled "Change in MAPSE During Treatment of Sepsis". Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the for...
What is the current status of trial NCT05634733?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2023-04-01. Estimated completion is 2030-12-01.
What conditions does trial NCT05634733 study?
This clinical trial studies the following conditions: Sepsis.
What interventions are being tested in trial NCT05634733?
The interventions under investigation include: Treatment of Sepsis (OTHER).
Who is sponsoring clinical trial NCT05634733?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05634733 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sepsis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05634733's enrollment target sits among peer trials
50 72nd of 90 higher than 16 of 90 other Sepsis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sepsis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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