Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05628805 · ClinicalTrials.gov registry record · NA
Theta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome
A NA study, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT05628805 is a NA study that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 16 participants.
The verdict
NCT05628805, a NA study, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Decades of Tourette Syndrome (TS) neuroimaging research has revealed abnormal cortical and subcortical motor system network, hypothesized to result from maladaptive plasticity. Repetitive transcranial magnetic stimulation (\[r\]TMS) is a promising technology that utilizes the concept of neuroplasticity to modulate brain circuits. TMS modulation has the distinct advantage in terms of its non-invasive nature. Furthermore, unique stimulation paradigms such as intermittent theta-burst repetitive TMS (iTBS) allows for short stimulation time (\<3 min). Using a sham-controlled protocol, the investigators propose modulating pre-SMA output using iTBS, based on our prior data of abnormal pre-SMA-mediated motor system regulation. hypothesize pre-SMA modulation results in increased pre-SMA-mediated motor inhibition. Enhancing these inhibitory measures with pre-SMA-iTBS provides the basis for improving inhibitory function in TS patients, leading to our long-term goal of neuro-stimulation to achieve clinical tic reduction.
Interventions
- DEVICE iTBS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2022-11-01 |
| Est. Completion | 2026-02-16 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05628805
The ClinicalTrials.gov registry entry for NCT05628805 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which iTBS is the first listed.
NCT05628805 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05628805 about?
NCT05628805 is a clinical study titled "Theta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome". Decades of Tourette Syndrome (TS) neuroimaging research has revealed abnormal cortical and subcortical motor system network, hypothesized to result from maladaptive plasticity. Repetitive transcranial magnetic stimulation (\[r\]TMS) is a promising technology that utilizes the concept of neuroplastic...
What is the current status of trial NCT05628805?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2022-11-01. Estimated completion is 2026-02-16.
What interventions are being tested in trial NCT05628805?
The interventions under investigation include: iTBS (DEVICE).
Who is sponsoring clinical trial NCT05628805?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.