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NCT05625659 · ClinicalTrials.gov registry record · NA

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

A NA study of Breast Cancer, sponsored by American College of Radiology.

Recruiting
Registry status
NA
Development phase
2,032
Enrollment target
11
Study locations

NCT05625659: Recruiting NA study of Breast Cancer, sponsored by American College of Radiology.

NCT05625659 is a NA study of Breast Cancer that is actively recruiting participants, run by American College of Radiology. The registered enrollment target is 2,032 participants, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (27% lower). The trial reports 11 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05625659, a NA study of Breast Cancer, is actively recruiting participants, sponsored by American College of Radiology.

RECRUITING
Registry status
NA
Development phase
2,032 participants
Enrollment target
11
Study locations

Study Summary

The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives than digital breast tomosynthesis (DBT) in women with dense breasts. Aim 1: To evaluate the performance of CESM compared to DBT at baseline for breast-cancer screening in women with dense breasts. Aim 2: To evaluate the performance of CESM compared to DBT at the 1-year follow up for breast-cancer screening in women with dense breasts.

Conditions Studied

Interventions

  • DIAGNOSTIC_TEST Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)

Study Locations (11)

Florida

  • Boca Raton Regional Hospital - Christine E. Lynn Women's Health and Wellness Institute - Boca Raton
  • Lake Medical Imaging - The Villages

Alabama

  • University of Alabama, Birmingham - Birmingham

Massachusetts

  • Boston Breast Diagnostic Center - Wellesley Hills

Michigan

  • Henry Ford Health - Detroit

New York

  • Memorial Sloan Kettering Cancer Center - New York

North Carolina

  • Carolina Breast Imaging Specialists - Greenville

Pennsylvania

  • Thomas Jefferson University Hospital - Philadelphia

Texas

  • The University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 2,032 participants
Start Date 2023-03-24
Est. Completion 2027-07-31
Phase NA

Sponsor

American College of Radiology

14 total trials

What the Registry Record Tells You About NCT05625659

The ClinicalTrials.gov registry entry for NCT05625659 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 2,032 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (27% lower). The listed sponsor is American College of Radiology, which has 14 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Dual-Energy Contrast-Enhanced Spectral Mammography (CESM) is the first listed.

NCT05625659 reports 11 study locations spanning 10 distinct geographic areas - top geographies include Florida, Alabama, Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05625659 about?

NCT05625659 is a clinical study titled "Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts". The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives than digital breast tomosynthesis (DBT) in women with dense breasts. Ai...

What is the current status of trial NCT05625659?

This trial is currently recruiting. It is a NA study. The enrollment target is 2,032 participants. The study started on 2023-03-24. Estimated completion is 2027-07-31.

What conditions does trial NCT05625659 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT05625659?

The interventions under investigation include: Dual-Energy Contrast-Enhanced Spectral Mammography (CESM) (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05625659?

This trial is sponsored by American College of Radiology, which has 14 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05625659 being conducted?

This trial has 11 study locations across Alabama, Florida, Massachusetts, Michigan, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.