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NCT05617040 · ClinicalTrials.gov registry record · Phase 1
Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer
A Phase 1 study, sponsored by Barinthus Biotherapeutics.
- Terminated
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT05617040: Clinical Trial Phase 1 study, sponsored by Barinthus Biotherapeutics.
NCT05617040 is a Phase 1 study that was terminated before completion, run by Barinthus Biotherapeutics. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05617040, a Phase 1 study, was terminated before completion, sponsored by Barinthus Biotherapeutics.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
This is a multi-centre, Phase 1/2, open-label clinical trial of the VTP-850 prime-boost immunotherapeutic in men with biochemical recurrence after definitive local therapy for prostate cancer.
Primary Outcome
Participants with AEs, ≥Grade 3 AEs, and serious adverse events.
Interventions
- BIOLOGICAL ChAdOx1-PCAQ
- BIOLOGICAL MVA-PCAQ
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2023-01-30 |
| Est. Completion | 2025-02-05 |
| Phase | Phase 1 |
Why NCT05617040 stopped before completion
NCT05617040 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 2 interventions - of which ChAdOx1-PCAQ is the first listed.
NCT05617040 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05617040 about?
NCT05617040 is a clinical study titled "Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer". This is a multi-centre, Phase 1/2, open-label clinical trial of the VTP-850 prime-boost immunotherapeutic in men with biochemical recurrence after definitive local therapy for prostate cancer.
What is the current status of trial NCT05617040?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2023-01-30. Estimated completion is 2025-02-05.
What interventions are being tested in trial NCT05617040?
The interventions under investigation include: ChAdOx1-PCAQ (BIOLOGICAL), MVA-PCAQ (BIOLOGICAL).
Who is sponsoring clinical trial NCT05617040?
This trial is sponsored by Barinthus Biotherapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05617040's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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