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NCT05614895 · ClinicalTrials.gov registry record · Phase 1
A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections
A Phase 1 study, sponsored by Hoffmann-La Roche.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT05614895: Completed Phase 1 study, sponsored by Hoffmann-La Roche.
NCT05614895 is a Phase 1 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05614895, a Phase 1 study, has completed, sponsored by Hoffmann-La Roche.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
The main aim of the study is to investigate the plasma pharmacokinetics (PK) and safety of intravenous (IV) administration of a single dose of 400 milligrams (mg) or 600 mg RO7223280 in critically ill participants with bacterial infections.
Interventions
- DRUG RO7223280
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2022-12-03 |
| Est. Completion | 2024-01-13 |
| Phase | Phase 1 |
What the finished NCT05614895 record still lists
NCT05614895 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 1 intervention - of which RO7223280 is the first listed.
NCT05614895 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05614895 about?
NCT05614895 is a clinical study titled "A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections". The main aim of the study is to investigate the plasma pharmacokinetics (PK) and safety of intravenous (IV) administration of a single dose of 400 milligrams (mg) or 600 mg RO7223280 in critically ill participants with bacterial infections.
What is the current status of trial NCT05614895?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2022-12-03. Estimated completion is 2024-01-13.
What interventions are being tested in trial NCT05614895?
The interventions under investigation include: RO7223280 (DRUG).
Who is sponsoring clinical trial NCT05614895?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05614895's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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