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NCT05609552 · ClinicalTrials.gov registry record
Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET
A clinical trial, sponsored by Johns Hopkins University.
- Completed
- Registry status
- 10
- Enrollment target
NCT05609552: Completed study, sponsored by Johns Hopkins University.
NCT05609552 is a clinical trial that has completed, run by Johns Hopkins University. The registered enrollment target is 10 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05609552 has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- 10 participants
- Enrollment target
Study Summary
This is an observational study that will examine the pretomanid pharmacokinetics (PK) in tuberculosis (TB) patients. Dynamic 18F-pretomanid PET/CT will be performed after intravenous injection of 18F-pretomanid to determine multi-compartment, noninvasive determination of pretomanid PK in TB patients.
Primary Outcome
Exposures in infected sites (pneumonia, cavitary lesions, etc.) will compared with the uninfected compartments. Standard units such as area under the curve (AUC) or AUC ratios will be utilized.
Interventions
- COMBINATION_PRODUCT 18F-Pretomanid PET/CT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2023-05-22 |
| Est. Completion | 2025-10-28 |
What the finished NCT05609552 record still lists
NCT05609552 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which 18F-Pretomanid PET/CT is the first listed.
NCT05609552 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05609552 about?
NCT05609552 is a clinical study titled "Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET". This is an observational study that will examine the pretomanid pharmacokinetics (PK) in tuberculosis (TB) patients. Dynamic 18F-pretomanid PET/CT will be performed after intravenous injection of 18F-pretomanid to determine multi-compartment, noninvasive determination of pretomanid PK in TB patients...
What is the current status of trial NCT05609552?
This trial is currently completed. The enrollment target is 10 participants. The study started on 2023-05-22. Estimated completion is 2025-10-28.
What interventions are being tested in trial NCT05609552?
The interventions under investigation include: 18F-Pretomanid PET/CT (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT05609552?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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