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NCT05606965 · ClinicalTrials.gov registry record · Phase 2

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Adults

A Phase 2 study, sponsored by ModernaTX.

Completed
Registry status
Phase 2
Development phase
172
Enrollment target

NCT05606965: Completed Phase 2 study, sponsored by ModernaTX.

NCT05606965 is a Phase 2 study that has completed, run by ModernaTX. The registered enrollment target is 172 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05606965, a Phase 2 study, has completed, sponsored by ModernaTX.

COMPLETED
Registry status
Phase 2
Development phase
172 participants
Enrollment target

Study Summary

The main purpose of the study is to evaluate the safety, reactogenicity, and the humoral immunogenicity of mRNA-1010 and comparator influenza vaccines against homologous influenza A and B strains at Day 29.

Interventions

  • BIOLOGICAL Inactivated Influenza Vaccine
  • BIOLOGICAL mRNA-1345
  • BIOLOGICAL mRNA-1010
  • BIOLOGICAL Egg-based Quadrivalent Influenza Vaccine
  • BIOLOGICAL Adjuvanted Quadrivalent Influenza Vaccine

Trial Details

FieldValue
Enrollment Target 172 participants
Start Date 2022-11-02
Est. Completion 2025-11-13
Phase Phase 2
ModernaTX

90 total trials

What the finished NCT05606965 record still lists

NCT05606965 is an interventional study that assigns participants to a tested intervention. The registered 172 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher).

The record links to 0 conditions, and to 5 interventions - of which Inactivated Influenza Vaccine is the first listed.

NCT05606965 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05606965 about?

NCT05606965 is a clinical study titled "A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Adults". The main purpose of the study is to evaluate the safety, reactogenicity, and the humoral immunogenicity of mRNA-1010 and comparator influenza vaccines against homologous influenza A and B strains at Day 29.

What is the current status of trial NCT05606965?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2022-11-02. Estimated completion is 2025-11-13.

What interventions are being tested in trial NCT05606965?

The interventions under investigation include: Inactivated Influenza Vaccine (BIOLOGICAL), mRNA-1345 (BIOLOGICAL), mRNA-1010 (BIOLOGICAL), Egg-based Quadrivalent Influenza Vaccine (BIOLOGICAL), Adjuvanted Quadrivalent Influenza Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT05606965?

This trial is sponsored by ModernaTX, which has 90 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05606965's enrollment target sits among peer trials

172 397th of 2000 higher than 1,603 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05606965, the US trial registry maintained by the National Library of Medicine. NCT05606965 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.