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NCT05602818 · ClinicalTrials.gov registry record · Phase 1
A Study of Soticlestat in Healthy Adult Nondependent Recreational Drug Users With Central Nervous System (CNS) Depressant Experience
A Phase 1 study, sponsored by Takeda.
- Completed
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
NCT05602818: Completed Phase 1 study, sponsored by Takeda.
NCT05602818 is a Phase 1 study that has completed, run by Takeda. The registered enrollment target is 100 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05602818, a Phase 1 study, has completed, sponsored by Takeda.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
Study Summary
The main aim is to evaluate the relative abuse potential of soticlestat in healthy adults who has used central nervous system (CNS) depressants for recreational nontherapeutic reasons.
Primary Outcome
Drug liking ("at this moment") assessed how much a participant likes or dislikes a drug effect at the time the question was being asked. It was scored using a 0 to 100-point bipolar VAS, where 0: Strong disliking, 50: Neither like nor dislike (neutral point), 100: Strong liking. A higher score indicates stronger liking.
Interventions
- DRUG Placebo
- DRUG Alprazolam
- DRUG Soticlestat 300 mg
- DRUG Soticlestat 600 mg
- DRUG Soticlestat 900 mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-11-15 |
| Est. Completion | 2023-07-07 |
| Phase | Phase 1 |
What the finished NCT05602818 record still lists
NCT05602818 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT05602818 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05602818 about?
NCT05602818 is a clinical study titled "A Study of Soticlestat in Healthy Adult Nondependent Recreational Drug Users With Central Nervous System (CNS) Depressant Experience". The main aim is to evaluate the relative abuse potential of soticlestat in healthy adults who has used central nervous system (CNS) depressants for recreational nontherapeutic reasons.
What is the current status of trial NCT05602818?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2022-11-15. Estimated completion is 2023-07-07.
What interventions are being tested in trial NCT05602818?
The interventions under investigation include: Placebo (DRUG), Alprazolam (DRUG), Soticlestat 300 mg (DRUG), Soticlestat 600 mg (DRUG), Soticlestat 900 mg (DRUG).
Who is sponsoring clinical trial NCT05602818?
This trial is sponsored by Takeda, which has 408 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05602818's enrollment target sits among peer trials
100 546th of 2000 higher than 1,411 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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