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NCT05594745 · ClinicalTrials.gov registry record · Phase 4

Treatment Regimens in Meibomian Gland Dysfunction

A Phase 4 study, sponsored by Tauber Eye Center.

Completed
Registry status
Phase 4
Development phase
60
Enrollment target

NCT05594745: Completed Phase 4 study, sponsored by Tauber Eye Center.

NCT05594745 is a Phase 4 study that has completed, run by Tauber Eye Center. The registered enrollment target is 60 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05594745, a Phase 4 study, has completed, sponsored by Tauber Eye Center.

COMPLETED
Registry status
Phase 4
Development phase
60 participants
Enrollment target

Study Summary

This study seeks to explore the relevance of inflammation in dry eye patients with MGD and compare the efficacy of LipiFlow treatment followed by lid hygiene and lubricant treatment with Systane Ultra or LipiFlow treatment followed by lid hygiene and lifitegrast treatment in patients with meibomian gland dysfunction.

Primary Outcome

visual analog scale from 0 to 100, higher is worse

Interventions

  • DRUG Lifitegrast Ophthalmic
  • DRUG Systane Free
  • DEVICE Lipiflow

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2021-03-02
Est. Completion 2023-01-21
Phase Phase 4
Tauber Eye Center

2 total trials

What the finished NCT05594745 record still lists

NCT05594745 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).

The record links to 0 conditions, and to 3 interventions - of which Lifitegrast Ophthalmic is the first listed.

NCT05594745 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05594745 about?

NCT05594745 is a clinical study titled "Treatment Regimens in Meibomian Gland Dysfunction". This study seeks to explore the relevance of inflammation in dry eye patients with MGD and compare the efficacy of LipiFlow treatment followed by lid hygiene and lubricant treatment with Systane Ultra or LipiFlow treatment followed by lid hygiene and lifitegrast treatment in patients with meibomian ...

What is the current status of trial NCT05594745?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2021-03-02. Estimated completion is 2023-01-21.

What interventions are being tested in trial NCT05594745?

The interventions under investigation include: Lifitegrast Ophthalmic (DRUG), Systane Free (DRUG), Lipiflow (DEVICE).

Who is sponsoring clinical trial NCT05594745?

This trial is sponsored by Tauber Eye Center, which has 2 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05594745's enrollment target sits among peer trials

60 1125th of 2000 higher than 799 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05594745, the US trial registry maintained by the National Library of Medicine. NCT05594745 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.