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NCT05586152 · ClinicalTrials.gov registry record · Phase 1
Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease
A Phase 1 study of Dry Eye Disease, sponsored by Invirsa.
- Completed
- Registry status
- Phase 1
- Development phase
- 84
- Enrollment target
- 1
- Study location
NCT05586152: Completed Phase 1 study of Dry Eye Disease, sponsored by Invirsa.
NCT05586152 is a Phase 1 study of Dry Eye Disease that has completed, run by Invirsa. The registered enrollment target is 84 participants, below the 252-participant average among 33 other Dry Eye Disease trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05586152, a Phase 1 study of Dry Eye Disease, has completed, sponsored by Invirsa.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 84 participants
- Enrollment target
- 1
- Study location
Study Summary
Phase 1/2, first-in-human, 2-part study to assess topically administered eyedrops of INV-102 during 2-week repeat dosing in subjects with moderate symptomatic dry eye disease. Part 1 will be a Dose Escalation phase across 4 cohorts of subjects to assess safety and tolerability of INV-102, and Part 2 will be an Optional Dose Expansion phase in a fifth cohort of subjects, pending the outcome of Part 1, to assess efficacy of INV-102 in the treatment of moderate symptomatic dry eye disease.
Primary Outcome
The primary endpoint in Part 1 of this First-in-Human (FIH) study was treatment-emergent adverse events (TEAEs) assessed across multiple dosing concentrations and dosing regimens.
Conditions Studied
Interventions
- DRUG Vehicle
- DRUG INV-102
Study Locations (1)
New York
- iuvo BioScience - Rush
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 84 participants |
| Start Date | 2022-08-30 |
| Est. Completion | 2023-05-02 |
| Phase | Phase 1 |
What the finished NCT05586152 record still lists
NCT05586152 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, below the 252-participant average among 33 other Dry Eye Disease trials with a reported enrollment target (67% lower).
The record links to 1 condition, with Dry Eye Disease appearing as the primary indexed condition, and to 2 interventions - of which Vehicle is the first listed.
NCT05586152 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05586152 about?
NCT05586152 is a clinical study titled "Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease". Phase 1/2, first-in-human, 2-part study to assess topically administered eyedrops of INV-102 during 2-week repeat dosing in subjects with moderate symptomatic dry eye disease. Part 1 will be a Dose Escalation phase across 4 cohorts of subjects to assess safety and tolerability of INV-102, and Part 2...
What is the current status of trial NCT05586152?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 84 participants. The study started on 2022-08-30. Estimated completion is 2023-05-02.
What conditions does trial NCT05586152 study?
This clinical trial studies the following conditions: Dry Eye Disease.
What interventions are being tested in trial NCT05586152?
The interventions under investigation include: Vehicle (DRUG), INV-102 (DRUG).
Who is sponsoring clinical trial NCT05586152?
This trial is sponsored by Invirsa, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05586152 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Dry Eye Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05586152's enrollment target sits among peer trials
84 26th of 33 higher than 8 of 33 other Dry Eye Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dry Eye Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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