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NCT05586152 · ClinicalTrials.gov registry record · Phase 1

Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease

A Phase 1 study of Dry Eye Disease, sponsored by Invirsa.

Completed
Registry status
Phase 1
Development phase
84
Enrollment target
1
Study location

NCT05586152 is a Phase 1 study of Dry Eye Disease that has completed, run by Invirsa. The registered enrollment target is 84 participants, below the 252-participant average among 33 other Dry Eye Disease trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05586152, a Phase 1 study of Dry Eye Disease, has completed, sponsored by Invirsa.

COMPLETED
Registry status
Phase 1
Development phase
84 participants
Enrollment target
1
Study location

Study Summary

Phase 1/2, first-in-human, 2-part study to assess topically administered eyedrops of INV-102 during 2-week repeat dosing in subjects with moderate symptomatic dry eye disease. Part 1 will be a Dose Escalation phase across 4 cohorts of subjects to assess safety and tolerability of INV-102, and Part 2 will be an Optional Dose Expansion phase in a fifth cohort of subjects, pending the outcome of Part 1, to assess efficacy of INV-102 in the treatment of moderate symptomatic dry eye disease.

Conditions Studied

Interventions

  • DRUG Vehicle
  • DRUG INV-102

Study Locations (1)

New York

  • iuvo BioScience - Rush

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2022-08-30
Est. Completion 2023-05-02
Phase Phase 1

Sponsor

Invirsa

4 total trials

What the Registry Record Tells You About NCT05586152

The ClinicalTrials.gov registry entry for NCT05586152 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 84 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 252-participant average among 33 other Dry Eye Disease trials with a reported enrollment target (67% lower). The listed sponsor is Invirsa, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Dry Eye Disease appearing as the primary indexed condition, and to 2 interventions - of which Vehicle is the first listed.

NCT05586152 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT05586152 about?

NCT05586152 is a clinical study titled "Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease". Phase 1/2, first-in-human, 2-part study to assess topically administered eyedrops of INV-102 during 2-week repeat dosing in subjects with moderate symptomatic dry eye disease. Part 1 will be a Dose Escalation phase across 4 cohorts of subjects to assess safety and tolerability of INV-102, and Part 2...

What is the current status of trial NCT05586152?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 84 participants. The study started on 2022-08-30. Estimated completion is 2023-05-02.

What conditions does trial NCT05586152 study?

This clinical trial studies the following conditions: Dry Eye Disease.

What interventions are being tested in trial NCT05586152?

The interventions under investigation include: Vehicle (DRUG), INV-102 (DRUG).

Who is sponsoring clinical trial NCT05586152?

This trial is sponsored by Invirsa, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05586152 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.