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RECRUITING Phase 2

Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED).

NCT07264517 · View on ClinicalTrials.gov ↗

Study Summary

This is a Phase 2, multi-site, double-masked, randomized, vehicle-controlled, study designed to evaluate the safety, tolerability, and efficacy in adult participants with DED.

Conditions Studied

Interventions

  • DRUG GRF312 5%
  • OTHER Placebo Comparator

Study Locations (10)

California

  • GC2302 Study Site 110 — Glendale
  • GC2302 Study Site 109 — Grove
  • GC2302 Study Site 103 — Newport Beach

North Carolina

  • GC2302 Study Site 104 — Asheville
  • GC2302 Study Site 101 — Garner

Georgia

  • GC2302 Study Site 105 — Morrow

Indiana

  • GC2302 Study Site 106 — Carmel

Pennsylvania

  • GC2302 Study Site 107 — Cranberry Township

Tennessee

  • GC2302 Study Site 102 — Memphis

Texas

  • GC2302 Study Site 111 — San Antonio

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2025-11-03
Est. Completion 2026-11-14
Phase Phase 2

Sponsor

Instituto Grifols, S.A.

2 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07264517

The ClinicalTrials.gov registry entry for NCT07264517 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Instituto Grifols, S.A., which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Dry Eye Disease appearing as the primary indexed condition, and to 2 interventions — of which GRF312 5% is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07264517 reports 10 study locations spanning 7 distinct geographic areas — top geographies include California, North Carolina, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07264517 about?

NCT07264517 is a clinical study titled "Evaluating the Safety, Tolerability, and Efficacy of GRF312 5% in Participants With Dry Eye Disease (DED).". This is a Phase 2, multi-site, double-masked, randomized, vehicle-controlled, study designed to evaluate the safety, tolerability, and efficacy in adult participants with DED.

What is the current status of trial NCT07264517?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2025-11-03. Estimated completion is 2026-11-14.

What conditions does trial NCT07264517 study?

This clinical trial studies the following conditions: Dry Eye Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07264517?

The interventions under investigation include: GRF312 5% (DRUG), Placebo Comparator (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07264517?

This trial is sponsored by Instituto Grifols, S.A., which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07264517 being conducted?

This trial has 10 study locations across California, Georgia, Indiana, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial