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NCT05584722 · ClinicalTrials.gov registry record
Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals
A clinical trial of Idiopathic Pulmonary Arterial Hypertension and Heritable Pulmonary Arterial Hypertension, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT05584722 is a study of Idiopathic Pulmonary Arterial Hypertension and Heritable Pulmonary Arterial Hypertension that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 150 participants, below the 665-participant average among 3 other Idiopathic Pulmonary Arterial Hypertension trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05584722, a study of Idiopathic Pulmonary Arterial Hypertension and Heritable Pulmonary Arterial Hypertension, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Pulmonary arterial hypertension (PAH) is a severe disease with a delayed diagnosis and markedly elevated mortality. High-risk populations, such as those with known genetic defects, provide a unique opportunity to determine the features of susceptibility and resilience to PAH. This proposal will fundamentally overturn the prevailing understanding of PAH by creating molecularly-driven signatures of susceptibility and resilience, provide novel insight into disease severity, and potentially identify new therapeutic targets. Funding Source - FDA OOPD
Conditions Studied
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2022-11-01 |
| Est. Completion | 2026-08-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05584722
The ClinicalTrials.gov registry entry for NCT05584722 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 665-participant average among 3 other Idiopathic Pulmonary Arterial Hypertension trials with a reported enrollment target (77% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Idiopathic Pulmonary Arterial Hypertension appearing as the primary indexed condition, and to 0 interventions.
NCT05584722 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT05584722 about?
NCT05584722 is a clinical study titled "Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals". Pulmonary arterial hypertension (PAH) is a severe disease with a delayed diagnosis and markedly elevated mortality. High-risk populations, such as those with known genetic defects, provide a unique opportunity to determine the features of susceptibility and resilience to PAH. This proposal will fund...
What is the current status of trial NCT05584722?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2022-11-01. Estimated completion is 2026-08-31.
What conditions does trial NCT05584722 study?
This clinical trial studies the following conditions: Idiopathic Pulmonary Arterial Hypertension, Heritable Pulmonary Arterial Hypertension, Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo, Healthy Individuals With no Cardiopulmonary Disease.
Who is sponsoring clinical trial NCT05584722?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05584722 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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