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NCT05574465 · ClinicalTrials.gov registry record · NA
Esophageal Manometry During Recovery From Endotracheal Intubation
A NA study, sponsored by University of California, San Francisco.
- Not yet
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT05574465: Clinical Trial NA study, sponsored by University of California, San Francisco.
NCT05574465 is a NA study that has not yet begun recruiting, run by University of California, San Francisco. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05574465, a NA study, has not yet begun recruiting, sponsored by University of California, San Francisco.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
1. An intact pharyngoesophageal reflex is essential to protect the upper airway from aspiration of either mouth contents or regurgitated gastric refluxate. This reflex is essential at protecting the airway in all patients. 2. In patients, while under medication to tolerate endotracheal intubation, it is postulated that an identifiable upper esophageal sphincter and esophageal peristalsis are not present. 3. With the cessation of anesthetics, accompanied by the reversal of nerve block, normal pharyngoesophageal peristaltic activity correlates with awakening the patient from anesthesia. This would be identified by the performance of esophageal manometry. 4. A return of normal verbally stimulated pharyngoesophageal swallowing sequence accurately identifies a safe time to remove endotracheal tubes and/or reverse anesthesia. This verbally stimulated swallowing sequence correlated precisely with the return of objective pharyngoesophageal function.
Interventions
- DEVICE High resolution solid state manometry
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-07-01 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
What is known before NCT05574465 opens enrollment
NCT05574465 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which High resolution solid state manometry is the first listed.
NCT05574465 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05574465 about?
NCT05574465 is a clinical study titled "Esophageal Manometry During Recovery From Endotracheal Intubation". 1. An intact pharyngoesophageal reflex is essential to protect the upper airway from aspiration of either mouth contents or regurgitated gastric refluxate. This reflex is essential at protecting the airway in all patients. 2. In patients, while under medication to tolerate endotracheal intubation, i...
What is the current status of trial NCT05574465?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-07-01. Estimated completion is 2027-12-31.
What interventions are being tested in trial NCT05574465?
The interventions under investigation include: High resolution solid state manometry (DEVICE).
Who is sponsoring clinical trial NCT05574465?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05574465's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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