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NCT05567952 · ClinicalTrials.gov registry record · Phase 2

A Study to Learn About a Repeat 5-Day Treatment With the Study Medicines (Called Nirmatrelvir/Ritonavir) in People 12 Years Old or Older With Return of COVID-19 Symptoms and SARS-CoV-2 Positivity After Finishing Treatment With Nirmatrelvir/Ritonavir

A Phase 2 study, sponsored by Pfizer.

Completed
Registry status
Phase 2
Development phase
436
Enrollment target

NCT05567952 is a Phase 2 study that has completed, run by Pfizer. The registered enrollment target is 436 participants.

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The verdict

NCT05567952, a Phase 2 study, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 2
Development phase
436 participants
Enrollment target

Study Summary

The purpose of this study is to learn about the safety and effects of nirmatrelvir/ritonavir for the potential treatment of COVID-19 rebound. The study is seeking participants who: * Have completed treatment with nirmatrelvir/ritonavir * Have a rebound in COVID-19 symptoms * Are SARS-CoV-2 (COVID-19) positive All study medications will be taken 2 times a day by mouth for 5 days. The first dose of study medication is taken at the study clinic and the rest at home. We will examine the experiences of people receiving the study medicines to those who do not. This will help us determine if the study medicines are safe and effective. People taking part will be in this study for about 24 weeks. Enrolled participants will need to visit the study clinic at least 8 times during the study.

Interventions

  • DRUG nirmatrelvir
  • DRUG ritonavir
  • DRUG placebo for nirmatrelvir

Trial Details

FieldValue
Enrollment Target 436 participants
Start Date 2022-10-19
Est. Completion 2024-02-09
Phase Phase 2

Sponsor

Pfizer

1,845 total trials

What the Registry Record Tells You About NCT05567952

The ClinicalTrials.gov registry entry for NCT05567952 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 436 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which nirmatrelvir is the first listed.

NCT05567952 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05567952 about?

NCT05567952 is a clinical study titled "A Study to Learn About a Repeat 5-Day Treatment With the Study Medicines (Called Nirmatrelvir/Ritonavir) in People 12 Years Old or Older With Return of COVID-19 Symptoms and SARS-CoV-2 Positivity After Finishing Treatment With Nirmatrelvir/Ritonavir". The purpose of this study is to learn about the safety and effects of nirmatrelvir/ritonavir for the potential treatment of COVID-19 rebound. The study is seeking participants who: * Have completed treatment with nirmatrelvir/ritonavir * Have a rebound in COVID-19 symptoms * Are SARS-CoV-2 (COVID-...

What is the current status of trial NCT05567952?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 436 participants. The study started on 2022-10-19. Estimated completion is 2024-02-09.

What interventions are being tested in trial NCT05567952?

The interventions under investigation include: nirmatrelvir (DRUG), ritonavir (DRUG), placebo for nirmatrelvir (DRUG).

Who is sponsoring clinical trial NCT05567952?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.