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NCT05565092 · ClinicalTrials.gov registry record · Phase 2

Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease

A Phase 2 study, sponsored by Alexion Pharmaceuticals.

Terminated
Registry status
Phase 2
Development phase
2
Enrollment target

NCT05565092: Clinical Trial Phase 2 study, sponsored by Alexion Pharmaceuticals.

NCT05565092 is a Phase 2 study that was terminated before completion, run by Alexion Pharmaceuticals. The registered enrollment target is 2 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05565092, a Phase 2 study, was terminated before completion, sponsored by Alexion Pharmaceuticals.

TERMINATED
Registry status
Phase 2
Development phase
2 participants
Enrollment target

Study Summary

The primary objective of this study is to assess the safety and tolerability of ALXN1820 SC (subcutaneous) in participants with SCD (Sickle Cell Disease).

Interventions

  • DRUG ALXN1820

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2023-02-22
Est. Completion 2024-01-09
Phase Phase 2
Alexion Pharmaceuticals

162 total trials

Why NCT05565092 stopped before completion

NCT05565092 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which ALXN1820 is the first listed.

NCT05565092 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05565092 about?

NCT05565092 is a clinical study titled "Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease". The primary objective of this study is to assess the safety and tolerability of ALXN1820 SC (subcutaneous) in participants with SCD (Sickle Cell Disease).

What is the current status of trial NCT05565092?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2023-02-22. Estimated completion is 2024-01-09.

What interventions are being tested in trial NCT05565092?

The interventions under investigation include: ALXN1820 (DRUG).

Who is sponsoring clinical trial NCT05565092?

This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05565092's enrollment target sits among peer trials

2 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05565092, the US trial registry maintained by the National Library of Medicine. NCT05565092 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.