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NCT05562934 · ClinicalTrials.gov registry record · Phase 2

An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients.

A Phase 2 study, sponsored by Novartis Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
189
Enrollment target

NCT05562934 is a Phase 2 study that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 189 participants.

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The verdict

NCT05562934, a Phase 2 study, has completed, sponsored by Novartis Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
189 participants
Enrollment target

Study Summary

The purpose of this 20-week randomized double-blind study in patients with resistant hypertension (rHTN) is to evaluate the efficacy, safety, and tolerability, of different doses of XXB750 administered as subcutaneous (SC) injections, compared to placebo. Since all study participants will be patients with rHTN, all study treatments will be given on top of maximally tolerated background antihypertensive therapy recommended by international guidelines for treatment of HTN (i.e., a thiazide or a thiazide-like diuretic, an angiotensin converting enzyme inhibitor (ACEi) or an angiotensin receptor blocker (ARB), and a long-acting dihydropyridine calcium channel blocker (CCB).

Interventions

  • OTHER Placebo
  • BIOLOGICAL XXB750 drug

Trial Details

FieldValue
Enrollment Target 189 participants
Start Date 2022-11-08
Est. Completion 2024-08-27
Phase Phase 2

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT05562934

The ClinicalTrials.gov registry entry for NCT05562934 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 189 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT05562934 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05562934 about?

NCT05562934 is a clinical study titled "An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients.". The purpose of this 20-week randomized double-blind study in patients with resistant hypertension (rHTN) is to evaluate the efficacy, safety, and tolerability, of different doses of XXB750 administered as subcutaneous (SC) injections, compared to placebo. Since all study participants will be patient...

What is the current status of trial NCT05562934?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 189 participants. The study started on 2022-11-08. Estimated completion is 2024-08-27.

What interventions are being tested in trial NCT05562934?

The interventions under investigation include: Placebo (OTHER), XXB750 drug (BIOLOGICAL).

Who is sponsoring clinical trial NCT05562934?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.