Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05552274 · ClinicalTrials.gov registry record · Early Phase 1
FTIH of ECC4703 in Healthy Volunteers
A Early Phase 1 study, sponsored by Eccogene.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 75
- Enrollment target
NCT05552274: Completed Early Phase 1 study, sponsored by Eccogene.
NCT05552274 is a Early Phase 1 study that has completed, run by Eccogene. The registered enrollment target is 75 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (42% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05552274, a Early Phase 1 study, has completed, sponsored by Eccogene.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 75 participants
- Enrollment target
Study Summary
This is a Phase 1, randomized, double-blind, placebo-controlled, single ascending dose and multiple ascending dose study of ECC4703 in healthy volunteers and participants with treatment unnecessary LDL-C under 160 mg/dL
Primary Outcome
Safety Assessment evaluated through adverse events, laboratory evaluations, vital signs, ECGs, and physical examination.
Interventions
- DRUG Placebo
- DRUG ECC4703
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2022-08-16 |
| Est. Completion | 2023-10-26 |
| Phase | Early Phase 1 |
What the finished NCT05552274 record still lists
NCT05552274 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (42% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05552274 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05552274 about?
NCT05552274 is a clinical study titled "FTIH of ECC4703 in Healthy Volunteers". This is a Phase 1, randomized, double-blind, placebo-controlled, single ascending dose and multiple ascending dose study of ECC4703 in healthy volunteers and participants with treatment unnecessary LDL-C under 160 mg/dL
What is the current status of trial NCT05552274?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 75 participants. The study started on 2022-08-16. Estimated completion is 2023-10-26.
What interventions are being tested in trial NCT05552274?
The interventions under investigation include: Placebo (DRUG), ECC4703 (DRUG).
Who is sponsoring clinical trial NCT05552274?
This trial is sponsored by Eccogene, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05552274's enrollment target sits among peer trials
75 304th of 2000 higher than 1,690 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01535430 · 75 participants
Assessment of Eloquent Function in Brain Tumor Patients
- NCT01542879 · 75 participants · Phase 1
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
- NCT02232191 · 75 participants · Phase 2
Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients
- NCT02754544 · 75 participants · NA
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI