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NCT05549934 · ClinicalTrials.gov registry record · Phase 2
Ritlecitinib for Cicatricial Alopecia
A Phase 2 study, sponsored by Emma Guttman.
- Completed
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
NCT05549934 is a Phase 2 study that has completed, run by Emma Guttman. The registered enrollment target is 50 participants.
The verdict
NCT05549934, a Phase 2 study, has completed, sponsored by Emma Guttman.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
Study Summary
Alopecia could be subdivided into two main groups of diseases: non-scarring alopecia, such as male pattern baldness, or alopecia areata (AA), in which hair follicles are preserved, yet quiescent, and scarring alopecia, also known as cicatricial alopecia (CA), in which hair follicles are irreversibly destroyed. CA leads to scarred areas, most commonly on the scalp, that cannot re-grow hair. Despite being a long-term condition, that often has significant impact on patients' well-being, available effective treatments for these diseases are lacking. In addition, the molecular abnormalities causing CA are largely unknown. The research team will be administering a new investigational drug (a JAK3/TEC inhibitor), ritlecitinib, which has shown statistically significant improvement in scalp hair loss for AA patients in a proof of concept and phase 2b/3 studies (B7981015 AA study). This is an open-label clinical trial. CA patients will be asked to provide small samples of skin and blood throughout the treatment period, to find out how they respond to the drug, and to attempt to better understand these diseases.
Interventions
- DRUG PF-06651600
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-12-15 |
| Est. Completion | 2025-03-20 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05549934
The ClinicalTrials.gov registry entry for NCT05549934 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Emma Guttman, which has 4 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which PF-06651600 is the first listed.
NCT05549934 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05549934 about?
NCT05549934 is a clinical study titled "Ritlecitinib for Cicatricial Alopecia". Alopecia could be subdivided into two main groups of diseases: non-scarring alopecia, such as male pattern baldness, or alopecia areata (AA), in which hair follicles are preserved, yet quiescent, and scarring alopecia, also known as cicatricial alopecia (CA), in which hair follicles are irreversibly...
What is the current status of trial NCT05549934?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2022-12-15. Estimated completion is 2025-03-20.
What interventions are being tested in trial NCT05549934?
The interventions under investigation include: PF-06651600 (DRUG).
Who is sponsoring clinical trial NCT05549934?
This trial is sponsored by Emma Guttman, which has 4 total clinical trials registered on ClinicalTrials.gov.
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